Dihydrotestosterone ke hormone e matla ea thobalano ea banna. Ho banna, e hlophisitsoe ke ketso ea enzyme 5-alpha reductase ho testosterone. Boholo ba dihydrotestosterone bo hlahisoa litekong. 'Meleng oa mosali, hormone e' ngoe, e bitsoang androstenedione, e sebelisoa ho etsa dihydrotestosterone. E hlahisoa ke litšoelesa tsa adrenal.
Karolo e nyane e hlahisoa ke mae a bomme. Ka hara libopuoa tsa banna, DHT e khetha litšobotsi tsa kholo ea 'mele ea mocha nakong ea bongoaneng. Hormone ena e ikarabella bakeng sa boitšoaro ba potency le botona le botšehali, nts'etsopele ea tšoelesa ea senya. Karolo e phahameng ka ho fetisisa ea hormone ena e bonoa ka har'a metso ea moriri le letlalo la setho sa botona. Haeba dihydrotestosterone e phahame 'meleng oa motho, mafu a fapaneng a ka hlaha ka lebaka la sena.
Karolo ea dihydrotestosterone 'meleng oa motho
Pele u nahana ka lisosa tsa ho eketseha ha dihydrotestosterone ho banna le basali, ho bohlokoa ho ba le mohopolo o akaretsang oa karolo ea hormone ena 'meleng oa motho. Dihydrotestosterone, hammoho le lihormone tse ling tse ngata tsa banna, li na le tšusumetso e tobileng kholong ea 'mele ea monna, boteng ba moriri' meleng le sefahlehong, ho theoa le nts'etsopele ea liphatsa tsa lefutso le tšoelesa ea senya, boitšoaro ba thobalano, jj.
Liperesente tse phahameng ka ho fetisisa tsa hormone ena li etsoa ka liseleng tse fumanehang kantle ho meeli ea liteko. Likahare tsa dihydrotestosterone tse phahameng ka ho fetisisa ho banna, joalo ka ha li se li hlokometsoe, li bonoa letlalong la litho tsa ho ikatisa le li-follicles tsa moriri.
Ho banna, lihormone tsena li na le tšusumetso ho matlafatsong ea lisele tsa tšoelesa ea senya. Ketsahalong ea hore litaba tsa lihormone tsena li kheloha tloaelo, ho hlaha mafu a fapa-fapaneng, ho kenyeletsa le lihono tsa senya. Haeba boemo ba dihydrotestosterone ho banna bo phahama ho feta bo tloaelehileng, hangata bakuli ba joalo ba tloaetse ho fuoa li-inhibitors tsa 5-alpha reductase. Lithethefatsi tse joalo li thibela ho kopana ha 5-alpha reductase, ka lebaka leo litaba tsa dihydrotestosterone maling a banna li fokotsehang. Tloaelo ho banna e ipapisitse le lilemo le lintlha tse ling tse lokelang ho tsotelloa ha ho fetisoa tlhahlobo.
'Meleng oa mosali, tlhahiso ea dihydrotestosterone e etsoa ka har'a lisele tsa methapo ea kutlo. Har'a li-androgens tsa banna ke lihormone tse 5, tseo ho tsona feela testosterone le dihydrotestosterone li nang le phello e tobileng 'meleng. Lihormone tse 3 tse setseng li karolo ea sehlopha sa li-pro-hormone, ke hore, li qala ho ama 'mele kamora ho fetohela "testosterone".
Haeba dihydrotestosterone 'meleng oa mosali e phahama ho feta boemo bo lumelloang, ngoanana o tla qala ho ba le matšoao a hyperandrogenism, joalo ka:
- hirsutism ke lefu leo ho lona moriri o holang haholo le moo basali ba sa hlaheng,
- makhopho
- keketseho e kholo ea boholo ba clitoris.
Haeba hormone e lula e phahame ka tsela e tloaelehileng lilemong tsa bocha, banana ba ka ba le mathata a ho etsoa ha masapo (e ba ho ea ka mofuta oa monna), ho ba sieo ha ho ea matsatsing kapa tšitiso ea potoloho, lentsoe le ka fetoha monyebe. Ho basali ba baholo, dikahare tsa dihydrotestosterone tse phahameng ho feta tse tloaelehileng li ka lebisa kholong ea ho hloka thari le ho ba mosesane.
Haeba lihormone li se na bongata bo lekaneng, ho ka fuoa litokisetso tse khethehileng ho mokuli, ka mor'a ts'ebeliso eo a tla phahama ka eona. Ho kheloha ha dikahare tsa dihydrotestosterone ho tloha ho tloaelehileng ho ka ba ntho e ncha kapa ea fumaneha.
Ho basali le banna, kholo ea dihydrotestosterone e kaholimo ho e tloaelehileng e lebisa ho fokotseng kholo ea moriri, ho senyeha ha boemo ba bona le alopecia.
Tloaelo le ho kheloha
Ho fumana dikahare tsa dihydrotestosterone maling a banna le basali, ho etsoa tlhahlobo ea mali ea venous. Nakong ea tlhahlobo ena, seramu ea DHT e khethoa ka mokhoa oa enzyme immunoassay. Tloaelo ho basali le banna e fapana ho ea ka lilemo.
- ka hypergonadism,
- ha u ntse u sebelisa lithethefatsi tsa lihormone,
- le Prostate adenoma,
- nakong ea bokhachane ho basali,
- boteng ba neoplasms ka gonads le adrenal gust,
- le hirsutism.
Ho hlakisa mabaka ka lebaka la hore na lihormone ena e phahame hakae, ho hlahisoa tlhahlobo e khethehileng. Tlhatlhobo ena e ka abeloa maemong a latelang:
- ka litaba tse tlase tsa androgens,
- ka tekanyo e tlase ea 5 alpha reductase,
- ka ho fokotseha ha takatso ea thobalano le tlolo ea molao oa boitšoaro,
- boteng ba matšoao a ts'oaetso ea "Prostatic hyperplasia" (ho ruruha ho ntša metsi, ho holisa lesapo la senya, joalo-joalo).
- nakong ea kalafo ka meriana e nang le li-inhibitors tsa 5-alpha-reductase,
- ka lehata le kapele,
- ka ho fokotseha ha boholo ba lipelesa tse tona, setho sa botona se senang tlhaho, ho se be teng ha moriri meriring le mokokotlong.
- ka litlolo tsa ho ea matsatsing, ho ba teng ha makhopho le matšoao a seborrhea,
- lilemong tsa bocha nakong ea ho kena bohlankaneng kapa boroetsaneng.
Dihydrotestosterone le testosterone ke lihomere tse hokahaneng, ka hona, e le molao, litaba tse kahare tsa bobeli le tsa bobeli li hlahlojoa ka nako e le ngoe.
Ho sebelisa tlhahlobo ho fumana maloetse a fapaneng
Haeba boemo ba dihydrotestosterone maling bo phahamisitsoe, hona ho ka supa ho ba teng hoa mafu a itseng. Maemong a joalo, ho netefatsa tšoaetso, ho etsoa tlhahlobo bakeng sa litaba tsa DHT maling. Har'a maloetse a lebisang keketseho ea litaba tsa dihydrotestosterone ke:
- hypogonadism ho banna,
- benign Prostatic hyperplasia,
- mathata a lefutso la tlhahiso e 5 ea alpha-rectase,
- Morris syndrome (e bontšoa ke ho haelloa ke ts'oaetso ea li-androgens),
- ho haella ha li-androgens, ho halefisoa ke liphetoho tse amanang le lilemo - maemong a joalo, ho hloka matla ho hlaha ka potlako ho banna, mme libido e fokotseha ho basali.
Boteng ba benign Prostatic hyperplasia, tlhahlobo ea dihydrotestosterone e fanoa ho lekola boemo ba mokuli le taolo ea liphetoho ha o sebelisa meriana, e nang le li-inhibitors tsa 5-alpha reductase. Basali maemong a mangata ba fetisa tlhahlobo e joalo ho fumana sesosa sa ponahalo ea dermopathy ea hyperandrogenic.
Keketseho ea dihydrotestosterone ho banna: lisosa le mokhoa oa ho theola boemo
Bokhabane bo hlakileng, bohloka ba monna, matla a 'mele - boleng ba li-hormone tse hlahisoang' meleng oa monna (haholo-holo ka litekeng) tsa testosterone ha li hlahisoa ke liphetoho tsa enzymatic.
Hormone ena ke dihydrotestosterone, eo maemong a mang e ka fetisang litekanyetso tse tloaelehileng.
DHT e ameha ho thehoeng ha mofuta oa kakaretso oa palo ea monna e monyane, nts'etsopele ea litho tsa botona, gland ea prostate, moralo oa kholo ea moriri, botona le botšehali le boemo ba potency. Lithane, mesifa le masapo a skeleton li tšehelitsoe ke mosebetsi oa lihormone tsena.
Malebela mabapi le ho itukisetsa tlhatlhobo
Tlhahlobo bakeng sa litaba tsa dihydrotestosterone e lokela ho nkuoa hoseng, hantle ka ho fetisisa pakeng tsa lihora tse 8 le 11, ka mpeng e se nang letho. Pele o etsa tlhahlobo, o ka noella metsi. Ho molemo ho hana tšebeliso ea tee, kofi, soda le ho feta. Mantsiboeeng a pele ho tlhahlobo, ha ho kgothaletswe ho ja lijo tse mafura.
Matsatsi a 1-2 pele ho tlhahlobo ea mali bakeng sa dikahare tsa dihydrotestosterone, o hloka ho hana ho noa joala le koae, o se ke oa phahamisa lintho tse boima, o se ke oa bapala lipapali tse mafolofolo. Ho khothalletsoa ho khaotsa ho sebelisa meriana ena, empa sena se lokela ho lumellanoa pele le ngaka.
Halofo ea hora pele ho tlhahlobo ea mali, mokuli o hloka ho theola moea, ho phomola hantle le ho phomola. Maemo a sithabetsang le ho tlakoloha maikutlong mathoasong a ho hlahlojoa ho hlahisitsoe.
Ha ho khonehe ho etsa tlhahlobo ea mali bakeng sa dihydrotestosterone kamora lithuto tsa ultrasound le x-ray, mekhoa ea ho silila le ea mmele, jj.
Liteko tsa litaba tsa testosterone li fuoa makhetlo a 'maloa ka linako tse itseng.
Ho hlokomela sephetho sa kalafo, tlhahlobo e 'ngoe le e' ngoe e latelang e lokela ho fanoa maemong a tšoanang, sebakeng se le seng le ka nako e le 'ngoe.
Haeba, nakong ea tlhahlobo ea dihydrotestosterone, motho a ke ke a emisa ho sebelisa meriana, u lokela ho tsebisa ngaka ea hau, hobane lithethefatsi tse ling li ka sotha litholoana tsa tlhahlobo.
Basali ba etsoa liteko tse ntle ka ho fetisisa tsa dehydrotestosterone qalong ea khoeli.
Phekolo e etsoa joang?
Taba ea hore tekanyo ea DHT e phahame e ka khethoa feela ke ngaka ka mor'a tlhahlobo e batsi ea liphetho tsa liteko. Ho latela liphetho, ho tla fanoa kalafo e nepahetseng. Maemong a mangata, ho fanoa ka litlhare tse fapaneng tsa lihormone. Lithethefatsi tse ikhethileng le nako ea kalafo e khethoa ke ngaka.
Ho lokela ho hopoloa hore ho se leka-lekane ha lihormone ho ka baka mathata a tebileng a bophelo bo botle. Ka keketseho ea boemo ba dihydrotestosterone maling, ho hlokahala kalafo e loketseng le e nakong. Kahoo arabela lipontšo tsohle tsa 'mele oa hau mme u se ke oa lieha ho etela sepetlele. Mahlohonolo ebe o phela hantle!
E arolelana ho eena le metsoalle 'me ka sebele ba tla arolelana ho hong ho ho khahlisang le ho nang le thuso ho uena! Ho bonolo haholo ebile e potlakile, ebile e bonolo. tlanya Konopo ea tšebeletso eo u e sebelisang khafetsa:
Tlhahisoleseling ka kakaretso le mesebetsi ea dihydrotestosterone
Dihydrotestosterone e kopantsoe ke ho hokahana ha enzyme 5-alpha reductase (5-AP) le testosterone, ka lebaka leo liathomo tsa 2 tsa haedrojene li kenyellelitsoeng morao-rao (ke ka lebaka leo "dihydro"). Testosterone ea mahala haholoanyane, ke ka mokhoa o sebetsang oa eona o sebetsang. Hoo e ka bang 70% ea DHT e thehiloe liseleng tse ka morao. Ho fapana le testosterone, dihydrotestosterone e hokahana le li-androgen receptor makhetlo a 3-4 ho feta ka mafolofolo, e etsa moralo o tsitsitseng le bona, e netefatsang sephetho sa eona se tsebahalang haholoanyane ka har'a mahloriso a fokolang (10% ea boemo ba testosterone bo potoloha maling). Boholo ba DHT bo kenelletse mefuteng ea moriri, letlalong la 'mele oa inguinal le ea senya. Boikoetliso bo phahameng ka ho fetisisa bo bonahala bokong, liphatseng tsa lefutso le letlalong.
Mesebetsi ea mantlha ea dihydrotestosterone:
- Li-receptor tsa androgen tse sebetsang li fumanoa ka bongata bo boholo liseleng tsa methapo, ka hona dihydrotestosterone e na le phello e ntle ea taolo ts'ebetsong ea tsamaiso ea methapo e bohareng,
- Khothaletso ea densation le kholo ea mesifa ea mesifa ka lebaka la tsamaiso ea methapo (testosterone e na le phello e tsebahalang haholoanyane ea anabolic),
- E ikarabella bakeng sa moriri oa mofuta oa banna, ts'ebetso ea gland ea sebaceous,
- E eketsa ho hanyetsa khatello ea maikutlo le ea kelello,
- E laola boleng ba libido le erection.
Mosebetsi oa bohlokoa oa dihydrotestosterone 'meleng oa monna ke ts'ireletso ea estrogen. DHT e thibela mosebetsi oa aromataseka ho nka karolo ha tsona le li-androgen tse fetotsoe li-estrogener.Banna ba nkang li-inhibitors tsa 5-AR hangata ba hlokomela lipontšo tsa gynecomastia (katoloso ea sefuba) - ka lebaka la khaello ea DHT.
Dihydrotestosterone ho banna e boetse e laola ts'ebetso ea karohano ea lisele tsa lisele tsa Prostate, ka hona, ho fetella ha lihormone tsena ho lebisa ho hyponplasia ea gland le ho fokola ha eona ka oncological.
Matšoao le lisosa tsa tlhekefetso
Tekanyetso e tloaelehileng ea dihydrotestosterone (boleng ba litšupiso) ho banna ba baholo ke 250 - 990 pg / ml. Mabapi le pontšo eo ka tlase ho tloaelehilenge supa matšoao a 'maloa:
- Ho lieha ho kena lilemong tsa bocha.
- Phokotso ea bophahamo ba mesifa, ho hlahisa mafura lethekeng le mpeng, ho eketsoa ha sefuba.
- Libas li fokotsehile, li mpefala le ho feta.
- Ho felisoa kapa ho fokotseha ha kholo ea moriri oa 'mele.
Hypogonadism ea mantlha le ea Bohlokoa e ka Lebisa Lipalo tsa Dihydrotestosterone tse tlase - ho haella ha li-androgens ka lebaka la li-pathologies tsa tlhaho kapa tse fumanoeng. Lintlha tse ling:
- Li-inhibitors tsa 5-AR Ba bang ba na le bofokoli ba tlhaho ba enzyme ena,
- Hypogonadism,
- Andropause (ho fokotseha ho amanang le lilemo tsa tlhaho maemong a testosterone).
Oho boemo bo phahameng Matšoao a latelang a bontša dihydrotestosterone:
- Pejana. DHT e feteletseng e baka methapo ea methapo ea moriri, ka lebaka leo moriri o fetohang 'mala, o ba mosesane ebe oa oa. Ho feta moo, whisky le mokokotlo oa hlooho ea hau li batla li sa utloe bohloko, ho senyeha ha moriri ho qala ka phatla le karolo ea parietal. Boikutlo ba lisele tsa bulb ho dihydrotestosterone bo ikemiselitsoe ka liphatsa tsa lefutso le ho fetisoa ka mola oa bo-mme ("gene ea baldness" - Sox21).
- Letlalo le nang le mafura a mangata haholo, ponahalo ea makhopho ("Makhopho a Hormonal"). Ho eketseha ha dihydrotestosterone ho halefisa sebaceous gland (hantle haholo, lisele tsa eona - sebocyte, holim'a eona ho na le li-androgen receptors) ho tlhahiso e matla ea sebum. Ka lebaka leo, pore e koaleha, ka hona e theha tikoloho e ntle bakeng sa nts'etsopele ea libaktheria.
- Letšoao la letlalo.
Banna ba nang le dihydrotestosterone e ngata hangata ba fapane ho ba mabifi ho sa utloahaleng, ho ba bohale, ho se leka-lekane.
E tsosang mabaka a dihydrotestosterone e phahameng ke:
- Moriana oa steroid
- Morris Syndrome (ho haella ha karabelo ho li-androgens),
- Tumellano ea litsoelesa tsa bohlohlo le li-testicles,
- Hypergonadism
- Prostate adenoma.
Haeba ho na le matšoao a bontšang ho leka-lekana ha dihydrotestosterone, o lokela ho ikopanya le urologist, andrologist kapa ngaka e akaretsang.
Ts'oaetso
Boikemisetso ba tekanyo ea dihydrotestosterone bo etsoa ka enzyme e kopantsoeng le immunosorbent assay ea venous mali (ELISA). Litsenyehelo tsa thuto li ipapisitse le boemo ba setsi sa bongaka le sebaka seo e leng ho sona. Karolelano theko ke 1300 p. Liphetho tsa tlhahlobo ea dihydrotestosterone li ka fumanoa kamora matsatsi a 7-9.
Matšoao a fumanoang ke lefu lena ke:
- Ho belaela ha adenoma kapa tlhokeho ea ho laola boemo ba tšoelesa ea senya nakong ea kalafo ea hyperplasia.
- Alopecia (baldness).
- Matšoao a ho haella kapa ho ata ha li-androgens.
Melao ea ho itokisetsa tlhahlobo:
- Lihora tse 8 pele ho sampole ea mali, u ka noella metsi a se nang likhabote feela, ho kenella lijo le lino tse ling ntle le ona.
- Halofo ea hora pele ho tlhahlobo, ha ua tšoanela ho sithabetsa maikutlo le ho tsuba moeeng.
- Qoba joala le lino tse tahiloeng ka letsatsi.
Ho bohlokoa ho bolella ngaka ea hau ka ho nka testosterone kapa 5-alpha-reductase inhibitors. Bakeng sa bohloeki ba sephetho, kalafo ea 'nete ka li-agents tsena e ka sitisoa.
Haeba dihydrotestosterone e kheloha ho ea ka tloaelo, ho fanoa ka litlhahlobo tse eketsehileng: ultrasound ea litho tsa pelvic, Prostate, testicles.
Maano a kalafo a khethoa ke liphetho tsa lefu lena, lilemo tsa mokuli le ho ba teng ha li-pathologies tse lumellanang.
Ho etsahalang ka teka-tekano le ho leka-lekana
Ka palo e lekaneng ea DHT, monna o itshwara ka botshepehi, o hodile hantle mmeleng, mmele o tiisitsoe, mesifa e thehiloe ka tsela e tloaelehileng. Mafura a mangata ha a thehoa.
Haeba lihormone li sa lekana, banna ba na le takatso e tlase ea thobalano. Ho eketseha ha dihydrotestosterone ho hlahisa ho se leka-lekane mokhatlong oa li-hormone, ho qobella li-receptors tse amehang boteng ba tsona ho arabela.
'Me kaha e kenelletse haholo mefuteng ea moriri le letlalong la litho tsa botona, ho se leka-lekane ha dihydrotestosterone' meleng oa monna ho bontšoa ke ho lahleheloa ke moriri, ka linako tse ling lefu la tsoekere le lefu la tšoelesa ea senya, ha ho etsoa maqhubu (ho fihlela mofetše ka mofetše oa senya).
Maemo a khatello ea maikutlo a hlalosoa hangata ke dihydrotestosterone e sa feleng, eo monna a neng a sa tsebe ka eona.
Lintho tse amanang le tlhaho
Mekhoa ea 'mele kapa maloetse ao dihydrotestosterone e phahamisoang ho ona:
- Phekolo ka lithethefatsi tsa lihormone, ho kenyelletsa le boemo ba qoqotho ea lihormone.
- Lintho tsa lefutso, joalo ka hypergonadism.
- Prostate adenoma ho banna.
- Microadenoma ea boko (pituitary gland).
- Ts'ebetso ea "tumor" ea botona.
- Hepatoplastoma.
- Ts'ebetso e sa lekaneng ea ts'ebetso ea sebete kapa lits'ebetso ho litšoelesa tsa adrenal.
Haeba ho basali ho tlola ho DHT ho ka qholotsoa ke litekanyetso tsa Postinor, joale ho banna boemo bo tebile le ho feta.
Matšoao a bonoang ka ntle ha a na kotsi - ho se leka-lekane, ha dihydrotestosterone e eketseha kapa e fokotseha, e ka ba seipone sa liketsahalo tse hlahang ka morao ho mmele, ka linako tse ling se beha bophelo kotsing.
Ho thibela nts'etsopele ea maloetse a tebileng, ela hloko lipontšo leha e le life tsa ho hloka toka ha li qala ho hlaha feela. Lefu le fumanoeng ka nako e fumanehang le phekoleha habonolo ebile le potlakile ho feta ha le ne le qala.
Ho eketseha ha hormone ho ka bonoa le prostate adenoma.
Empa dihydrotestosterone e phahame ho banna eseng kamehla mabapi le bokuli bo tebileng. Ka linako tse ling ho kheloha ho tloaelehileng ho tlalehiloe ha mokuli a etsoa kalafo le 5-alpha-reductase inhibitors (palo ea eona e hokahane le tlhahiso ea DHT).
Haeba ho fumanoa hore boemo ba dihydrotestosterone bo phahame, hammoho le mabaka a ileng a bo susumetsa, ho hlokahala hore hang-hang u qale kalafo le ho theola letšoao.
Hoa hlokahala ho fokotsa boleng ho ea ka tloaelo ea monna oa hormone ena, e nang le phapang ka lilemo.
Tloaelo ea dihydrotestosterone ea banna e mefuta e fapaneng ea 25-990 pg / ml, ho nka feela lintlha tse utloisisang tsa setsebi, ka hona ho khothaletsoa haholo hore u se ke ua itlhahloba.
Ikopanye le tleliniki moo o lulang teng - hona ho tla potlakisa tlhahlobo eo le ho u sireletsa ho tsoa lits'ebetsong tsa methapo ea methapo.
Tharollo ea mathata
Phekolo ha e so ithute mokhoa oa ho thibela menyetla ea ho senyeha ha li-hormone, empa kalafo e nakong e ka potlakisa boemo ba mokuli.
Ke lokela ho ea ho ngaka efe? Ka litaba tse phahameng tsa dihydrotestosterone ho banna, likhothaletso li fanoa ke litsebi - urologist le endocrinologist.
Mokhoa oa ho theola sekhahla sa DHT, haholo ho latela sesosa sa ho eketseha ha eona, litšobotsi tsa setšoantšo sa kliniki le boemo ba litho tse ling tsa mmele oa mokuli.
Mokhoa oa phekolo o lula o le mong, hobane mekhoa ea endocrine e bobebe ebile e hokahane. Ke setsebi sa endocrinologist feela se nang le tsebo se ka khethang mefuta eohle ea lintlha tse hokahaneng.
Khafetsa o ne a tloaetse ho beoa ha lithethefatsi tsa lihormone tse nkang ho feto-fetoha ha maemo ho sa leka-lekanang ha lihomone tsa mokuli.
Ho fapana le basali, bao maemong a joalo ho nang le pheko e le 'ngoe feela - Diane 35, bakuli ba banna ba phekoloa ka botlalo, ba sebelisa mekhoa e fapaneng ea kalafo.
Ka ho eketseha ha hormone, ho kgothaletswa ho ikopanya le urologist kapa endocrinologist.
Ntle le moo, banna ba nang le maemo a phahameng a DHT ba ka laeloa ho nka inhibitors (inhibitors) ho 5-alpha reductase. Har'a tsona ke Buserelin, Deslorelin. Ba thusa ho fokotsa dihydrotestosterone. Mekhoa e meng ea meriana e ka etsahalang ke Medroxyprogesterone, Spironolactone. Ketonazole Empa likhetho tsena tsohle li lokela ho etsoa feela ke ngaka e tlang.
Hopola kotsi ea ho lematsa bophelo ba hau ka ho itlhalosa e le ntho e fetang lefu le leng teng.
Joalo ka litlhare tsa tlholeho, o ka sebelisa limela tsa antiandrogenic tsa meriana tse fokotsang tlhahiso le tlhahiso ea DHT:
- Lipeo tsa mokopu le tee e tala.
- Mafura a flaxseed le stevia.
- Vithamine C, B6 le fireweed.
- Milk thistle le fenugreek.
Haeba setšoantšo sa lefu le tlatselletsoa ke botenya, lijo tse nang le lik'habohaedreite tse ngata li kenyellelitsoe ho bopeng lithethefatsi. Ka nako e 'ngoe esita le tekanyo ena e nyane e kenya letsoho ho tlatsetsa ho thateng ha maemo a lekanang la li-hormone.
Mensgen.ru »Lihormone» Hobaneng ho na le keketseho ea dihydrotestosterone le hore na e ka e fokotsa joang 'meleng oa monna
Dihydrotestosterone ho banna: mesebetsi, boemo bo tloaelehileng le ho kheloha
Dihydrotestosterone ho banna ke hormone e hlahisoang ho tsoa testosterone ka methapo ea kutlo ea enzymatic. Ho na le tse ling phapang lipakeng tsa testosterone ledihydrotestosteronetse amang ts'ebetso ea lihormone 'meleng. DTG e laola tšebetso e tloaelehileng ea tšoelesa ea senya le litho tsohle tsa tsamaiso ea genitourinary.
Dihydrotestosterone E ikarabellang bakeng sa ponahalo e nakong ea litšoaneleho tsa bobeli tsa thobalano ho bahlankana le botsofaling, khatello ea eona 'meleng e ka fetoha.
Ho fapoha ha boemo ba lihormone ho latela tloaelo ho ka supa li-pathologies tse fapaneng, ka hona ho bohlokoa ho ithuta khafetsa le ho hlokomela maemo a DHT maling.
Fumana dihydrotestosterone — engke 'Me o na le bohlokoa bofe ho monna, o ka ea ho urologist.
Mesebetsi ea Dihydrotestosterone
Phapang ke efe? testosterone e tsoang ho dihydrotestosterone, le hore na li-hormone tse joalo li etsa mesebetsi efe 'meleng? Dihydrotestosterone ke hormone e hlahisoang ho banna.
Ha e bapisoa le testosterone, e sebetsana le ho feta le li-receptor tsa cellular, kahoo ts'ebetso ea eona ea androgenic e bonahala haholo.
Ntho e joalo e na le tšusumetso e kholo ntlafatsong le tšebetsong ea tšoelesa ea senya nakong e tlang, ka hona, ho tsa bongaka e sebelisoa haholo ho felisa mafu a tšoelesa ea senya.
Ketsahalong ea ha khatello ea dihydrotestosterone 'meleng oa monna e eketseha haholo mme e feta litekanyetso tse lumelletsoeng, joale ho na le keketseho e hlokomelehang ka boholo ba tšoelesa ea senya. Ntle le moo, li-pathologies tse fapaneng li qala ho ntlafala 'me sebopeho se kang seboko merianeng ea tšoelesa ea senya se fumanoa.
Khokahano ea dihydrotestosterone e hlahisoa ke tlhahiso le dikahare tsa testosterone 'meleng oa monna. Phahameng ea litaba tsa morao-rao, tekanyo ea eona e kholo e tšeletsoe ho DHT. Hoa hlokahala ho boloka boemo bo tloaelehileng ba hormone e joalo ka lebaka la taolo ea testosterone, tlhahiso ea eona e laoloang ke hypothalamus le gland ea pituitary.
Dihydrotestosterone e sebetsa ka mafolofolo kholisong le mesebetsing ea litho tse ling hape e na le phello e tobileng lits'ebetsong tsa likokoana-hloko le 'mele. Hormone e joalo e laola boemo ba liphatsa tsa lefutso, mesifa, mesifa ea moriri le tsamaiso ea marapo.
DHT e na le phello e ntle ntlafatsong ea 'mele lilemong tsa bocha eseng feela karolong ea matšoao a bobeli. Hormone e joalo e thusa ho potlakisa sebopeho sa mesifa le ho bola ha mafura. DHT e ama boits'oaro ba monna ba thobalano, ka lebaka leo, ho haella ha 'mele oa hae e ba sesosa sa ho hloka matla le ho fokolisa libido.
Matšoao a khelohileng
Letšoao la pele le bonts'a seo ho eketseha ha dihydrotestosterone ho banna, ho ba le mathata a moriri.
Ka mantsoe a mang, moriri o oa tsoa, kholo ea bona ea kokobela ebe ka mor'a nako monna o fetoha lefatla.
Hormone e joalo 'meleng oa monna le eona e ama lisele le litho tse ling, ka hona, tlolo ea litaba tsa eona e tsamaisana le ponahalo ea matšoao a itseng.
Ho haelloa ke Hormone ho bashanyana ho baka mathata a maholo kholong ea thobalano. Ho bana ba joalo, moriri ha o hlahelle lintleng le likarolong tse ling tsa 'mele, hape ho na le litlolo ka sebopeho sa botoneng. Ntle le moo, ho na le khaello ea mmele ea mesifa, mme botona kapa bo-testicles bo fokotsoe ka boholo.
Ketsahalong eo dihydrotestosterone ho bannatheoleloa, joale ho ka hlaha basali, ho se sebetse hantle ha maoto le matsoho.
Ka tloaelo, bakuli ba joalo ba ikhethile har'a batho ba nang le tlhaho e bolaeang le e bohlasoa, 'me ba koalehile ka bobona.
Ho haella ha DHT ho banna ho lebisa ho fokotseha ha takatso ea thobalano le ho hloka botsitso ho fihlela mathata a erement.
Ketsahalong eo dihydrotestosterone e phahameng ho banna, ha ho letho le letle ho sena le lona le latelang. Ho banna, ho na le ho se leka-lekane ha lihormone, ho hola ha moriri hloohong hoa emisa 'me ho ba le sebali se mafolofolo hoa hlokomeleha.
Eketsa maemo a dihydrotestosterone ho banna leha e le ka pg / ml e mmalwa, e tsamaisana le mocha ea molelele haholo, tsoelo-pele ea moriri oa hae le letlalo le boreleli
Dihydrotestosterone le mmele oa mosali
Ho utloisisa karolo ea dihydrosterone 'meleng oa mosali, ho bohlokoa ho utloisisa hore na ke eng le hore e etsoa joang.
U tla lebala ka lefu la qoqotho haeba u noa khalase e le 1 hoseng.
Dihydrotestosterone - Ena ke li-hormone tsa banna, tseo hammoho le lihormone tsa basali, tse busoang ke mali. Androgen, i.e. lihorm tsa banna, e ea patoa adrenal cortex le ovarian e itseng. E thehiloe ho tsoa ho testosterone (hormone ea botona ba banna) ka ho nka karolo ha enzyme e khethehileng, karolo ea protheine - 5-alpha reductase.
Dihydrotestosterone e na le phello e matla ho feta testosterone mme e bohlokoa haholo ho mmele oa mosali.
Karolo ea DHT 'meleng oa basali:
- e nka karolo mosebetsing oa litšoelesa tsa sebaceous le taolo ea ho fufuleloa,
- ea ikarabellang bakeng sa kholo ea moriri, mesifa le masapo a mosali,
- e laola libido tsa basali,
- Ke karolo ea bohlokoa ea metabolism ea mafura, protheine le carbohydrate 'meleng.
Tloaelo ea dihydrotestosterone ho basali le banna
Ho tseba ho kheloha hofe kapa hofe ho hlahisoeng ha dihydrotestosterone 'meleng oa mosali kapa monna, litsebi li sebelisa matšoao a tloaelehileng. Khokahano ea dihydrosterone 'meleng oa mosali e ikemiselitse ho sebelisa tlhahlobo ea mali ea kliniki, joale matšoao a bapisoa le a tloaelehileng.
Lethathamo la litloaelo tsa letšoao la dihydrotestosterone ho banna le basali ka lilemo:
Ho basali ba lilemo tsa ho ba le bana, palo ea dihydrotestoster e nkoa e le palo e ka hare 24-250 pg / mlleha ho le joalo, nakong ea postmenopausal, letšoao lena le fokotsehile hanyane. Ketsahalo e phahameng ea "dihydrotestosterone" 'meleng e etsahala hantle nakong ea phetoho ea bongoana, ha ho kena bohlankaneng ho etsahala. Boemong bona, boemo ba dihydrotestosterone maling bo bohlokoa haholo, kaha androgen ena e ikarabella bakeng sa kholo ea 'mele e lumellanang.
Boemo bo eketsehileng ba Dihydrotestosterone
Bakeng sa ts'ebetso e tloaelehileng ea liphatsa tsa lefutso le litsamaiso tsohle tsa 'mele, ho leka-lekana ha li-hormone tsa banna le basali hoa ikarabella. Haeba boemo ba dihydrotestosterone ba 'mele' meleng oa mosali kapa ngoanana bo eketsehile, lits'ebetso tse ngata li hloleha. Mohlala, lilemong tsa bocha, banana ba bonts'a matšoao a pele a ho eketseha ha dihydrotestosterone 'meleng:
- makhopho a bocha, makhopho,
- ho ilela khoeli kapa ho ba sieo ha eona ka botlalo,
- Letlalo la banna le hlaha,
- ho thehoa lentsoe le thata.
Lintlha tsena ha se ho kheloha ho tloaelehileng, leha ho le joalo, haeba potoloho e sa fole ka mor'a lilemo tse peli, joale sena e ka ba letšoao la dihydrotestosterone e eketsehang.
Ho haelloa ke Hormonal tsa dihydrotestosterone hangata ho etsahala ha e se e le motho e moholo.
HoBasali ba nang le dihydrotestosterone e phahameng ba fumana matšoao a latelang:
- kholo ea moriri 'meleng, haholo sefahlehong, ka holim'a molomo o kaholimo e ea matlafatsoa
- mofufutso oa eketseha
- moriri o oa tsoa
- boima ba 'mele boa eketseha
- takatso e matla ea thobalano,
- boholo ba clitoris le labia boa eketseha
- letlalo le nang le bothata ba mafura.
Bohlokoa! Ho ba teng ha le leng la matšoao ana ho kanna ha se bonts'e boemo bo eketsehang ba dihydrotestosterone maling, empa ke a mang a mabaka a ho ea ngakeng.
Ho banna, matšoao a ka sehloohong a ho eketseha ha dihydrotestosterone ke ho kuta moriri le ho ba mabifi, ka lebaka la nts'etsopele ea adenoma ea botoneng kapa ho hloka thari. Ha e le 'mele oa mosali joalemabaka a keketseho ea dihydrotestosterone maling a bontša boteng ba li-pathologies tse latelang:
- androgenic adrenal tumor,
- mathata a metabolic 'meleng oa mosali,
- ovary ea polycystic,
- ho hloka thari
- lefu la tsoekere
- liphetoho tsa tlhaho kapa tse fumanoeng tsa methapo ea methapo ho hypothalamus (karolo ea diencephalon, e ikarabella mosebetsing oa lits'ebetso tse ngata 'meleng, ho kenyelletsa le adrenal gland).
Fokotsa dihydrotestosterone
Hape ho etsahala hore lihormone tsa qoqotho li hlahisoe hampe ho basali, boemo ba bona bo tlase haholo ho feta bo tloaelehileng.
Tekanyetso ea Dihydrotestosterone e fokotseha ka mabaka a 'maloa:
- khaello ea androgen
- Morris syndrome (mathata a amanang le botšehali kholisong ea thobalano).
- lefu la tsoekere.
Ho fokotseha ha litekanyetso tsa testosterone le dihydrotestosterone ho ka khethoa ke matšoao a kantle. Mohlala, ho banna ba nang le ho fokotseha ha dihydrotestosterone, ho fokotseha ha moriri, ho fokotseha ha boima ba mesifa, nts'etsopele e sa fetoheng ea likarolo tsa 'mele le botenya ba mofuta oa basali.
Ha e le basali, boemo bo fokotsehileng ba dihydrotestosterone bo bontšoa ke lintlha tse latelang:
- e fokotsitse takatso ea thobalano haholo,
- ho hloka boroko, mokhathala,
- letlalo le omeletseng.
Bohlokoa! Ke setsebi feela se tla tseba sesosa sa 'nete sa ponahalo ea matšoao a joalo ka ho hlahloba sephetho sa tlhahlobo ho bona hore na boemo ba dihydrotestosterone maling a mosali ke bofe. Mohlomong ho leka-lekana ha dihydrosterone ha ho tiisoe.
Ho itokisetsa tlhahlobo
Haeba u e-ea ngakeng ka matšoao a hlalositsoeng, o tla u laela hore u ee tlhahlobong ho fumana hore na dihydrotestosterone e maling ke eng.
Bakeng sa tlhahlobo ea tekanyo ea dihydrotestosterone ho bonts'a liphetho tse nepahetseng ka ho fetisisa, ho hlokahala hore u e lokisetse hantle:
- Tlhahlobo ea ho fumana tekanyo ea dihydrotestosterone ho basali e etsoa hantle ka mpeng e se nang letho. Haeba u sa khone ho ja ntle le lijo, motho o lumelloa ho noa tee kapa o ntse a le metsi. Lijo tsa mantsiboea tsa thuto e lokela ho ba tse bobebe, tse mafura a tlase le tse tlase.
- Matsatsi a mararo pele ho tlhahlobo ea boemo ba dihydrotestosterone maling, ho hlokahala hore o tlohele joala, ho tsuba le meriana e matla.
- Qoba maemo a sithabetsang.
- Tlhahlobo e ka fana ka sephetho se fosahetseng haeba mantsiboea a mokuli a entse ultrasound, x-ray, MRI kapa ho silila.
- Etsa bonnete ba hore u tsebisa setsebi ka ho nka meriana, nako eo u se nang tokelo ea ho e sitisa.
Ho nka basali nengho hlahlojoa ho molemo ha e le lilemo tsa ho tsoala. Ha ho hlahlojoa boemo ba dihydrotestosterone maling, ho lokela ho tsotelloa hore na ke letsatsi lefe la potoloho eo mosali a oang ka lona letsatsing lena.
Ts'ebetso e khethoa ka ho khetheha matsatsi a 2- 2 ka mor'a ho ilela khoeli. Kaha boemo ba lihormone bo amanang le mosebetsi oa ho ikatisa bo ka fapana ho latela maemo a kemolo.
Mehato ea kalafo
Tlolo leha e le efe ea semelo sa lihormone ho mosali e hloka kalafo e hlophisitsoeng, e tla fokotsa kapa ho eketsa boemo ba dihydrotestosterone. Leha ho le joalo, ho na le lisosa tse seng tsa 'mele tsa boemo bo phahameng kapa bo tlase ba dihydrotestosterone ho basali.
Tabeng ena, ho felisa mathata ana, nako (ea bongoaneng) le ho buisana khafetsa le ngaka e tla hlokomela lipontšo tsa matšoao a kantle ho phetoho ea dihydrotestosterone mme e ka qala kalafo e nakong ka nako ea haeba ho ka hlokahala hore ho be le ho leka-lekana ka nako e telele.
Ho hloka taolo ea dihydrotestosterone ho etsahala nakong ea kemero, ho khaotsa ho ilela khoeli le lithethefatsi tse itseng Goserelin, Danazol, Phenytoin le lithethefatsi tse ling. Ngaka e khetha lithethefatsi ka bonngoe ho mokuli ka mong le ho ipapisitse le sesosa sa ho hlobaela ha dihydrotestosterone 'meleng oa mosali.
Dihydrotestosterone le tahlehelo ea moriri li hokahane, kaha tlhahiso ea protheine e itšetlehile ka ho sebetsa ha li-follicles tsa moriri. Ka hona, mosali o qala ho fokola ebe moriri o oa tsoa. U ka theola boemo ba dihydrotestosterone joang ntlheng ee? Ho fokotsa androgen ho basali, ho fanoa ka litlhare tse khethehileng - li-blocker 5-alpha reductase.
Tse tloaelehileng haholoLithethefatsi tse fokotsang boemo ba dihydrotestosterone 'meleng oa mosali ke:
Phytoestrogens (phytohormones e hlahisoang limela) e thusa ho fokotsa tlhahiso ea dihydrotestosterone: litholoana tsa palema e pharalletseng, li-clover tse khubelu, soy, alfalfa, koena, chamomile, sage.
Nettle , joalo ka e 'ngoe ea mefuta ea li-phytoestrogens, e na le phello e molemo ho fokotseng boemo ba dihydrotestosterone ho basali. Lithibela-pelehi tsa molomo li boetse li sebetsa hantle ho phekoleng ho leka-lekana ha litekanyetso tsa DHT 'meleng oa mosali: Yarina, Janine, Diane-35.
Bohlokoa! Meriana e fokotsang boemo ba dihydrotestosterone ho mosali e na le phello e khutšoane, ke hore, nakong ea tsamaiso ea bona.
Ka polycystosis, haeba mosali a rera ho ima, ngaka e eang teng e ka fana ka litlatsetso tsa ovulation ho mokuli - tharollo ea methapo (Puregon, Menogon) kapa matlapa Klostilbegit.
Haeba boemo ba dihydrotestosterone ba mosali bo nyoloha ka lebaka la ho se lekane ha li-glucose tsa nama, ho ja lijo tse tlase tsa carb ho tla lekana ho theola boima ba 'mele. Kamora nako, botsitso ba lihormone bo tla ntlafala butle-butle ntle le tšebeliso ea meriana mme boemo ba tlhahiso ea dihydrotestosterone bo tla khutlela ho bo tloaelehileng.
Ka testosterone e tlase, hangata ngaka e beha litlhare tse tla thusa ho khutlisetsa polokeho ea 'mele ea mosali.
Maemong a mang, li-pathologies ha li phekolehe, moo maemo a dihydrotestosterone a lokelang ho lula a beiloe leihlo ke meriana.
Qeto
Basali ba bangata ba leka ho phekola tahlehelo ea moriri ka litlhare tsa batho, livithamini le mekgwa e fapaneng ea bohloeki, ba sa tsebe mathata a tebileng le ho feta ka tlhahiso ea dihydrosterone. Leha ho le joalo, kalafo ea matšoao ha e hlahise litholoana tsa nako e telele.
Ke ngaka-endocrinologist feela e ka fumanoang le ho fana ka thuso e tšoanelehang ka ho se leka-lekane ha li-hormone tsa dihydrotestosterone ho basali. U se ke ua inahanafatsa 'me u se ke ua hlokomoloha bophelo bo botle ba hau!
DHT e sebetsa ho basali le banna
Mesebetsi ea mantlha ea DHT 'meleng oa monna e amana le ho theha le ho holisa ts'ebetso ea kemolo le litšobotsi tsa thobalano. Dihydrotestosterone ho banna e na le litlamorao tse latelang:
- e tsosa spermatogenesis,
- inbits secretion ea hormone ea luteinizing ka hara gland ea anterior
- e ama mokhoa o sebetsang oa lisele tsa gonadotropic ho adenohypophysis,
- e susumetsa kholo ea tšoelesa ea senya le litho tsa ka ntle tsa botšehali nakong ea bokhachane, e phahamisa kholo ea bona ea ho kena bohlankaneng,
- e etsa mefuta ea bobeli ea thobalano,
- e laola sebopeho le nts'etsopele ea tsamaiso ea masapo, kholo ea mesifa,
- e na le tšusumetso e matla tsamaisong ea methapo,
- libido
- ea ikarabellang bakeng sa tlhahiso ea sebum,
- e ama li-follicles tsa moriri, e ikarabella bakeng sa kholo ea moriri oa thobalano.
DHT e boetse e hlahisoa 'meleng oa mosali. Mohloli o ka sehloohong oa tlhahiso ea dihydrotestosterone ho basali ke adrenal cortex, lisele tsa ovari, le phetoho ho tsoa ho li-hormone tsa pele tsa li-steroid ho sebete, mesifa, letlalo le lithane tsa adipose.
Mesebetsi ea DHT 'meleng oa basali:
- e ama lik'habohaedreite, protheine, metabolism ea mafura,
- e etsa qeto ea nts'etsopele ea masapo le marapo a marapo,
- laola ho fufuleloa,
- e kenya tšebetsong litšoelesa tsa sebaceous,
- e bopa libido.
Keketseho e kholo ka ho fetisisa maemong a dihydrotestosterone e bonoa nakong ea bongoana, tlhoro ea tlhahiso ea eona e oela ho lilemo tse 25. Ka lilemo, secretion ea li-hormone e ea fokotseha butle butle.
Tabeng ea mathata a ts'ebetso, ho ka khonahala ho leka-lekanya litekanyetso tsa li-hormone ntle le ts'ebetso ea bongaka ka thuso ea khalemelo ea bophelo.
- ho fihlela lilemo tse 10: 5-25 pg / ml ho banana le 5-50 pg / ml ho bashanyana,
- Ho tloha ho lilemo tse 10 ho isa ho 12: 24-450 pg / ml ho banana, 5-50 pg / ml ho bashanyana,
- ho tloha ho lilemo tse 13 ho isa ho 18: 24-450 pg / ml ho banana le 250-700 pg / ml ho bashanyana,
- ho tloha ho lilemo tse 18 ho isa ho tse 50: 24-450 pg / ml ho basali le 250-990 pg / ml ho banna,
- ho tloha lilemong tse 50: 10-181 pg / ml ho basali, 250-700 pg / ml ho banna.
Ho kheloha sephiring sa DHT ho ka lebisa ho tlolo e tebileng ea ts'ebetso ea litsamaiso tse fapaneng tsa 'mele.
E fokotsehile DHT
Khafetsa, boemo bo tlase ba hormone bo bonoa ho banna kamora lilemo tse 30-40.
Lisosa tsa ho fokotseha ha maemo a DHT ho banna
- botenya
- lefu la tsoekere
- 5 alpha reductase khaello
- khaello ea androgen
- hypogonadism (ho se lekane botšehali).
- ramatiki e sa foleng
- Morris syndrome (testicular feminization syndrome).
Matšoao a ho fokotseha ha maemo a DHT ho banna:
- li-depositi tsa mafura a basali (lirope, li-buttocks),
- e liehisa kholo ea thobalano ho bacha, kholo ea maoto le matsoho e sa fetoheng.
- nts'etsopele ea setšoantšo ho latela palo ea basali,
- boholo bo fokotsehileng ba botoneng, sebopeho sa eona e sa tloaelehang,
- ho hola ha moriri butle ka sefahleho, ka har'a meropa, likhukhuni,
- khatello ea maikutlo, lability ea maikutlo,
- mokhathala,
- ho haella ha mesifa
- ho hloka thipa, ho fokotsa ho ikoetlisa ka ho kopanela liphate
- bothata ba ho ba le bana, liphetoho ho spermogram.
Pathologies ea gland ea pituitary, mae a bomme, litšoelesa tsa adrenal, mafu a tsamaeang le khaello ea lithane tsa adipose a ka lebisa ho ntlafatso ea khaello ea androgen ho basali. Khaello ea DHT ho basali e tšoauoa ka ho fokotseha ha mesifa, mesifa ea maikutlo, tšekamelo ea khatello ea maikutlo, ho fokotseha ha libido le ho fokotseha ha molumo oa letlalo le botenya.
Ha dihydrotestosterone e phahamisoa
Maemo a phahamisitsoeng a dihydrotestosterone ho banna a ka supa mathata a latelang:
- adrenal gland tumor
- hlahala ea botona
- hlahala e bohloko le e bohloko ea tšoelesa ea senya
- hypergonadism (ts'ebetso e feteletseng ea lihormone ea gonads),
- lefu la pelo.
DHT e feteletseng e ka boela ea bakoa ke ho nka meriana e nang le androgens.
Mesebetsi ea mantlha ea DHT 'meleng oa monna e amana le ho theha le ho holisa ts'ebetso ea kemolo le litšobotsi tsa thobalano.
Matšoao a ho eketseha ha DHT ho banna:
Lisosa tse ka bang tsa ho eketseha ha li-hormone ho basali:
- li-adrenal tumors,
- lefu la tsoekere
- le li-tumor tse hlahisang androgen ka har'a litšoelesa tsa marenene kapa li-ovari,
- khaello ea phepo e nepahetseng, botenya
- pathology of the hypothalamus,
- ho sebelisa lithethefatsi tsa Hormone.
Keketseho ea 'mele kapa ho fokotseha hoa DHT e bonoa nakong ea bokhachane, ho basali ba pele le ba nakong ea bokhachane, nakong ea kemero le ho anyesa.
Haeba DHT e phahame, sena se ka fana ka tlhahiso ea li-pathologies tse ngata.Tekanyo e phahameng haholo ea DHT ho basali e tšoauoa ka matšoao a latelang:
- hirsutism
- Ho nyehlisa hlooho,
- ho ruruha ho feteletseng
- molumo oa lentsoe
- makhopho, seborrhea,
- mofuta oa skeleton male,
- botenya
- hypertrophy ea klitoris le labia,
- ho hloleha ho ea matsatsing
- ho hloka thari
Mohopolo oa li-hormone le ketso ea tsona
Pele u fumana hore na mabaka a ho eketseha ha dihydrotestosterone e ka ba eng le hore na o etsang ka hona, o lokela ho hopola lithuto tsa sekolo tsa anatomy. Kahoo, androgens e ata 'meleng oa banna.
Hona le mefuta e 5 ea li-androgens ka kakaretso. Ho feta moo, ke mefuta e 'meli feela ea androgen e nang le phello e tobileng ho thehoeng ha banna. Dihydrotestosterone ke hormone e nang le tšusumetso e tsebahalang haholo ho li-receptor.
Hormone ena e ikarabella ka mesebetsi e mengata.
- Kholo ea 'mele ea monna. Ebile, DHT e ikarabella ka mekhoa e mengata ea anabolic. Ka sekhahla se lekaneng sa li-hormone tsena maling, monna o boloka sebopeho sa tlhaho, ke hore, mahetla a sephara, thekeng le tšesaane. Dihydrotestosterone e boetse e ikarabella bakeng sa ho haha mesifa mme e kenya letsoho ho chesoeng ha mafura a subcutaneous.
- Boitšoaro ba thobalano. Ka dikahare tse lekaneng tsa DHT, monna o boloka erection e ntle le libido e phahameng. Haeba boemo ba li-hormone bo nyoloha kapa bo putlama, joale ho bona liphoso tse fapaneng.
- Boteng ba litšobotsi tsa bobeli tsa thobalano. Ka tloaelo lihormone tsa thobalano li thusa ho boloka lentsoe le tlaase, ponahalo ea moriri sefubeng le mpeng. Taba e khahlang ke hore keketseho ea dihydrotestosterone ho monna e baka balune.
- Ts'ebetso e tloaelehileng ea tšoelesa ea senya. Ka litaba tse eketsehileng tsa DHT maling, lisele tsa tšoelesa ea senya li qala ho hola. Tabeng ena, re se re ntse re bua ka prostate adenoma. Maemong a matla, ho hlaha hlahala e mpe.
Boleng bo tloaelehileng ba dihydrotestosterone ho banna ba lilemo tse 15 ke 250-990 pg / ml. Ka keketseho kapa ho fokotseha hoa matšoao ana, re se re ntse re bua ka pathology.
Hobaneng DHT e phahamisitsoe?
Maemo a ntseng a eketseha a dihydrotestosterone a bonoa ho banna ba sebelisitseng li-anabolic steroid bakeng sa ho theha mesifa. Ho lokela ho hopoloa hore ho kotsi haholo ho sebelisa lithethefatsi tsa lihormone ho sa hlokahale.
Sena se bakoa ke taba ea hore kamora 'nete e joalo, testosterone ea mahala e fetoloa estrogen, mme tlhahiso ea testosterone e fokotsehile. Boemo ba prolactin, estradiol le estrogen bo eketseha kamora ho nka li-anabolic steroids. Sena se ferekantsoe ke kholo ea ho hloleha ha li-hormone.
Ho qoba sena, ho molemo ho sebelisa li-boost tsa hlama ea tlhaho ho eketsa matšoao a matla. Li tla thusa ho eketsa matla le litekanyetso tsa mahala tsa testosterone maling ntle le ho lematsa. E amohelehang ka ho fetisisa ho tloha sebakeng sa polokeho ea pono ke boar boithuto ba Yarsagumba Forte.
Haeba dihydrotestosterone e phahame, ho ka ba le mabaka a mang:
- Lefu la Itsenko-Cushing. Poleloana ena e bolela bokuli boo ho bona ho thehoang sethoathoa sa 'mele.
- Ponahalo ea maqeba a mabe ka har'a tšoelesa ea adrenal. Empa keketseho ea DHT e ka hlokomeloa esita le maemong ao tumor ha e mpe.
- Testosterone toxicosis. Tlas'a poleloana ena, ho na le mofuta oa maloetse a hlahang moo motho a tsoaloang a amanang le lisele tsa Leydig.
- Benign Prostatic hyperplasia. Ha bokuli bona bo hlaha, mathata a letsoalo a bonoa. Maemong ohle, ho na le boemo bo eketsehang ba dihydrotestosterone. Ho feta moo, matšoao a ka eketseha ha nako e ntse e feta le maemong a qalang a ho nyoloha ha BPH.
Keketseho ea dihydrotestosterone ho banna e boetse e bonoa boteng ba Morris syndrome. Ho feta moo, ka bokuli bona, motho ea nang le chromosome ea Y a ka ba le botšehali bo holileng.
Matšoao le Ho Khetholla
Maemong moo dihydrotestosterone e phahamisitsoeng ho banna, feminization e shebiloe. Mokuli o na le ho fokotseha ho hoholo ha karolo ea karolo ea boima ba mesifa, ho fokotseha ho hola ha moriri sefahlehong le 'meleng le ho fokotseha ha libido. Hoo e batlang e le kamehla ho na le botoniki ba "flaccid penis" kapa "erectile dysfunction".
Maemong a tsoetseng pele a kliniki, setšoantšo se tsebahala le ho feta. Ho na le ho ruruha ha litšoelesa tse anyesang. Hangata, nipples e utloisa bohloko le ho hlohlona. Hoa etsahala hore keketseho ea DHT e ama letlalo. Mohlala, makhopho a sefahleho le lekhopho li ka hlaha letlalong.
Ho na le lisosa tse ngata tsa ho eketseha ha dihydrotestosterone ho banna. Ka hona, molao-motheo oa ts'oaetso o khethoa ka bomong ho latela liqeto tsa ngaka e eang. Empa maemong 'ohle, moo ho nang le matšoao a ts'ebetso ea botšehali, tlhahlobo e etsoa bakeng sa boemo ba DHT.
Hore tlhahlobo e ka tšeptjoa, mokuli o lokela ho:
- Se ke oa ja lijo ka letsatsi leo u lekang lihormone tsa thobalano. O ka nwa feela metsi ntle le khase.
- Matsatsi a 2-3 pele ho tlhahlobo, tlohela ho noa joala le ho tsuba.
- Matsatsi a 1-2 pele ho tlhahlobo, hana ho ja lijo tse mafura.
- Khaotsa ho sebelisa lithethefatsi tsa li-hormone le meriana e meng e ka khopisang sephetho sa tlhahlobo.
Ho latela sephetho sa liteko, ngaka e khetha sesosa sa keketseho ea DHT, mme e khetha kalafo e loketseng.
Seo u lokelang ho se etsa ka maemo a phahameng a DHT?
Ho phekola linyeoe tsa kliniki ha dihydrotestosterone ho banna e phahamisa, ho hlokahala ka mokhoa o phethahetseng. Haeba neoplasms ka har'a gland ea adrenal e fetoha sesosa sa ho eketseha ha DHT, kalafo ea kalafo e laetsoe. Haeba ho hlokahala, kalafo ea radiation le chemotherapy li sebelisoa kamora ts'ebetso.
Haeba ts'ebetso e eketsehileng ea 5-alpha-reductase e bonoa, 'me dihydrotestosterone e eketsoa, ho sebelisoa li-inhibitors tsa 5-alpha-reductase. Ka tloaelo, lithethefatsi tse kang Avodart, Finasteride, Dutasteride lia sebelisoa.
Ho fokotsa sekhahla sa DHT, lithethefatsi tse nang le phello ea antiandrogenic le tsona li ka sebelisoa. Ke a mefuta e 'meli:
- Steroidal. Li-antiandrogens tse sebetsang hantle tse tsoang sehlopheng sena ke Spironolactone, Cyproterone Acetate, Megestrol Acetate.
- E seng ya steroidal. Har'a li-anti-androgens tse seng li-steroidal, tse ntle ka ho fetisisa ke Casodex, Anandron, Flutamide.
Haeba DHT e phahame ho moshemane, joale ho sebelisoa li-analog tsa nako e telele tsa maiketsetso tse tsoetseng pele tsa Lutropin.
Phekolo ea litheko tse phahameng tsa DHT ka lebaka la lefu la Itsenko-Cushing, testosterone toxicosis, le anomalies eagengenic ea steroidogenesis e etsoa kalafo.
Empa eseng kamehla ka thuso ea lithethefatsi ho ka etsahala ho fumana sephetho se phahameng. Mohlala, lefu la Itsenko-Cushing le ka alafshoa ka kalafo ea adrenalectomy kapa proton. Sephetho se setle ka ho fetisisa se ka fumaneha ka ho sebelisa ts'enyo ea litšoelesa tsa adrenal ka ho hlahisa moemeli ea fapaneng ea senyang sebopeho sa bona.
Joalokaha u tseba, DHT e phahameng hangata e bakoa ke prostatitis le adenoma. Phekolo ea mafu ana a banna e etsoa kalafo. Bakeng sa sena, li-peptides tsa bioregulatory, lithibela-mafu, li-inhibitors tsa 5-alpha-reductase, li-alpha-1-adrenergic agents tse thibelang, li-analgesics, li-antispasmodics li sebelisoa.
Mokhoa oa ho theola dihydrotestosterone
Ho fokotsa maemo a dihydrotestosterone hoa hlokahala ho hatella tšebetso ea enzyme e e hlophisang - 5-alpha-reductase. Bakeng sa sena, ho sebelisoa mefuta e 'meli ea lithethefatsi (li-blockers tsa DHT): e thehiloe holima Finasteride le Dutasteride.
Finasteride ("Penester" le "Proscar" - matlapa a nang le 5 mg ea motsoako o sebetsang, "Propecia" - 1 mg) ke inhibitor e ikhethileng ea enzyme (li-block 5-alpha-reductase mofuta oa 2), e sebetsa hantle bakeng sa hyperplasia ea prostatic le alopecia. Ha Finasteride e sebelisoa, serum DHT e theoha ka 70%. Liphetho tsa kalafo ea ho theola boemo ba dihydrotestosterone lia bonahala kamora likhoeli tse 3 tsa tsamaiso - Ho fokotseha ho hoholo ha molumo oa prostate ho tsitsitse, botenya ba letlalo le sefahleho bo tloaelehile.
Fokotsa boemo ba dihydrotestosterone maling le liseleng tsa tšoelesa ea senya. E thibela phello e susumetsang ea DHT kholisong ea tšoelesa ea senya. Theko ea meriana ea litlhare e ka ba li-ruble tse 500
Bakeng sa litlamorao tse mpe tse tlisoang ke ho nka li-Finasteride, ho na le phokotso ea boima ba liapole tsa testicles, ho senyeha hoa morphology le sepheo sa spermatozoa, ponahalo ea khatello ea maikutlo le matšoenyeho a sa foleng. Haeba thupelo e hlakotsoe, matšoao a hyperplasia a khutla kamora likhoeli tse 6-8. Selemong sa pele sa kalafo, banna ba ka ba le ho hloka thari, ho fokotseha ho hoholo hoa libido ("postfinasteride syndrome"). Kamora kalafo ea lilemo tse 2-4, litla-morao tsena li lula li nyopa, empa eseng kamehla.
Dutasteride (Avodart, Urofil, Alfinal) ke inhibitor molokong oa 2; hang hang e thibela mefuta ea 1 le 2 ea 5-alpha reductase isoenzymes. Mefuta ea Dihydrotestosterone e fokotseha hanyane kamora libeke tse 1-2 tsa tsamaiso. Ntho ena e sebetsa hantle ho feta Finasteride − boemo ba serum dihydrotestosterone bo fokotsoe ke 95%. Lithethefatsi tse thehiloeng ho Dutasteride hangata li sebelisoa ho haha 'mele ho lekola litla-morao tsa androgenic tsa li-steroid tse ling (alopecia, lintlha tse eketsehileng tsa mafura a letlalo le sefahleho, makhopho). Empa ka nako e ts'oanang, phello e mpe e boetse e bonoa ka tsela ea ho fokotseha ha matla le mesifa ka kakaretso, le ho putlama ha potency. Banna ba bang ba qobelloa ho nka Viagra ka lebaka la khaello e matla ea erectile. Hape hoa khoneha nts'etsopele ea gynecomastia ka lebaka la khatello ea ts'ireletso ea antiestrogenic ea dihydrotestosterone. Litla-morao tse tloaelehileng tse tlisoang ke ho nka mefuta e 'meli ea li-blocker le tsona ke ho ruruha, ho hlohlona, hives, rashes.
Ntle le li-inhibitors tsa 5-alpha reductase ho fokotsa dihydrotestosterone maemong a mang, ho sebelisoa lintho tsa antiandrogenic: flutamide, spironolactone.
Joalo ka kalafo ea lehae bakeng sa kalafo ea ho sebelisa "baldness" "Minoxedil", e fumanehang ka mokhoa oa sephoqo kapa tharollo. Maemong a fetisisang, li-follicles tsa moriri li fetisetsoa ho tsoa libakeng tse ikemetseng tsa androgen.
Ho fokotsa boemo ba dihydrotestosterone ho banna ba banyane, lingaka li leka ho se sebelise lithethefatsi tsa lihormone, e le hore li se ke tsa qholotsa khaello ea androgen. Litlhare tsa setso le litlatsetso tsa phepo li ka thusa ho fokotsa boemo ba lihormone tse sebetsang:
- E khohlela letlapa
- Litholoana tsa palema ea palema e mpe: "Prostaplant", "Permikson", "Prostakur",
- Vithamine B le zinki le tsona li kenya letsoho ho fokotseha hoa ts'ebetso ea 5-alpha reductase. Ho ruisa 'mele ka lintho tsena lijong ho lokela ho kenyelletsa litlhapi, sebete sa nama ea khomo, linaoa, soya, peo ea mokopu.
Ka ho se sebetse hantle kapa ho sa sebelisoe hantle hoa kalafo e thibelang tlhaho, tšoelesa ea senya kapa ea adrenal neoplasms e tlosoa.
Eketsa dihydrotestosterone
Eketsa maemo a dihydrotestosterone ka testosterone e fokolisitsoeng e ka susumetsoa ke tlhahiso ea lihormone kapa ke tsamaiso ea li-steroids tsa kantle ho naha. Maemong a pele, ho sebelisoa chorionic gonadotropin, thioctic acid, lithethefatsi tsa antiestrogen tse thehiloeng ho Clomiphene citrate kapa tamoxifen.
Haeba phekolo e sa khaotseng ea phekolo e hlokahala, ho fanoa ka testosterone ea khale., e ka bang ka mokhoa oa liente, matlapa, li-gels, litlolo tsa lihormone kapa likatse tsa transdermal. Lithethefatsi tsa moloko oa ho qetela ke Nebido. Ho boloka boemo bo tloaelehileng ba testosterone (ka ho latellana, le dihydrotestosterone), ente e le 'ngoe ea likhoeli tse ling le tse ling tsa 3-4 e lekane. Melemo ea mantlha: ha ho na phello e mpe ho sebete, liphio le gland ea senya.
Ts'ebeliso ea letsatsi le letsatsi ea testosterone patches le li-gels (Androgel) e boetse e fana ka keketseho ea boemo ba androgens, empa liforomo tsena ha li bonolo haholo ka lebaka la tlhoko ea ho lokisa letlalo, menyetla ea ho teneha le ho se khonehe ha ho kopana le batho ba bang ba letlalo (ha u sebelisa litlolo le li-gels).
Haeba testosterone e tloaelehilengebe ho sebelisoa litokisetso tsa dihydrotestosterone (gel ea Andraktim, matlapa).
U ka etsa joang hore boemo ba DHT bo be bobebe?
Mokhoa o ka sehloohong oa ho phekola mathata a secretion ea DHT ke kalafo ea lithethefatsi. Lithethefatsi tse ikhethileng le nako ea kalafo e khethoa ke ngaka.
Ho fokotseha ha boemo ba dihydrotestosterone boikoetlisong ba bongaka ho etsoa ho sebelisoa li-androgenin tsa steroidal le tseo e seng tsa steroid. Lithethefatsi tsena li thibela sebopeho sa DHT kapa li thibela ho tlama ha eona ho fihlella li-receptor tsa sele. Tabeng ea ho fetoha thobalano pele ho nako baneng ba banna, ho sebelisoa li-agents tse ka fokotsang secretion ea lihormone tsa gland le hypothalamus. Haeba dihydrotestosterone e phahame ho basali, lithethefatsi tse nang le metformin le spironolactone li laetsoe. Ka ts'ebetso e eketsehileng ea li-inhibitors tsa 5-alpha reductase tsa enzyme ena li sebelisoa.
Haeba kheloha ea boemo ba lihormone ho latela tloaelo e amahanngoa le hlahala ea litšoelesa tsa "adrenal" kapa "testicles", "kalafo ea kalafo" kapa "radiop" e hlokahala.
Haeba boemo ba lihormone bo theotsoe, phekolo ea phekolo ea li-hormone e laetsoe.
Tabeng ea mathata a ts'ebetso, ho ka khonahala ho leka-lekanya li-hormone ntle le meriana ka thuso ea khalemelo ea mokhoa oa bophelo: ho bapala lipapali, ho lokisa boima ba 'mele, ho etsa mosebetsi o tloaelehileng le phomolo, ho tlohela mekhoa e mebe. Lijo tse nang le phepo e ntle li ka eketsa palo ea li-androgens - phepo e lokela ho matlafatsoa ka livithamini, liminerale le protheine. Ho bohlokoa ho qoba khatello ea kelello le maikutlo, joalo ka ha cortisol e lokollotsoeng nakong ea khatello ea maikutlo e thibela li-hormone tsa botona ba botšehali.
Video e tsoang ho YouTube ka sehlooho sa sengoloa:
Tloaelo ho basali
Ke eena ea fanang ka ntlafatso e lumellanang ea litho le litsamaiso, a fa monna ea nang le lipontšo le bokhoni ba monna, le mosali ea nang le basali.
Likarolo tsa kahare tsa secretion tsa bong ka bobeli li hlahisa "li-set" tsa lihormone, tse kenyeletsang ka bobeli li-estrogens (basali) le androgens (e motona).
Bohlokoa ba 'ngoe kapa bo bong bo khetholla bong ba motho.
Ho ba teng ha dihydrotestosterone ho basali hoa hlokahala bakeng sa taelo ea:
- Sebaka sa litšoelesa tsa sebaceous se sebetsa ho tiisa mofufutso o tloaelehileng,
- kholo le kholo ea masapo le mesifa,
- Ho etsoa le moriri o tloaelehileng,
- mefuta e fapaneng ea phapanyetsano,
- libido.
Hormone ena ea bohlokoa e patiloe ke mae a bomme le adrenal cortex. Letšoao le tloaelehileng la dihydrotestosterone 'meleng oa mosali le tloha ho 5 ho isa ho 450 pg / ml. Ho latela lilemo:
Keketseho ea palo ea lihormone tsa banna, ha sena e se lefu la kelello, e bonoang:
- nakong ea bokhachane ba banana, ha ho hlaha mekhoa ea bobeli ea thobalano,
- 'meleng oa basali baimana.
Kamano lipakeng tsa dihydrotestosterone le tahlehelo ea moriri ke tsona tse hlakileng ka ho fetisisa. Ke homone ena e lebisang banna ho kuta.
Mabapi le mabaka a ho fokotsa testosterone ho banna ba baliloeng mona.
Phapang ke efe lipakeng tsa testosterone ea mahala le e felletseng? Haeba o rata, bala sengoloa sena.
Mabaka a ho eketseha ha dihydrotestosterone
Lebaka la ho tlola ho sa lokang ha 'mele ho ea ka bongata ba lihomone tsa' mele oa motho e ka ba:
- ts'ebetso ea hlahala (mohlala, ovary ea polycystic),
- mathata a sebetsang tsamaisong ea endocrine,
- mathata a metabolism ea carbohydrate (ka mamello ea glucose),
- mathata a sebetsang a sebete a amanang le tlhahiso ea globulin, ho haella ha eona ho sa lumeleng litho le litsamaiso ho amohela lihormone tsa basali ka tekanyo e nepahetseng,
- ho sebelisa lithethefatsi tse nang le li-hormone.
Bophelo bo botle ba ovary le polycystic
Liphello e ka ba:
- Tlolo ea kemiso ea ho ea matsatsing ho fihlela ho se be teng ka ho felletseng hoa molao, ho etsang hore mohopolo o se khone,
- sebopeho sa musculoskeletal system ho ea ka mofuta oa monna,
- ponahalo ea makhopho a sefahleho le makhopho a khubameng a letlalo le sefahlehong, sefubeng le mokokotlong,
- molumo oa lentsoe
- ho eketsa mabifi
- tahlehelo ea moriri hloohong le kholo e kholo ea tsona libakeng tse sa tloaelehang ho basali: sefahlehong, sefubeng le mokokotlong,
- endometrial hyperplasia, ha boemo ba hae bo sa fetole liphetoho tse tloaelehileng tsa lekunutu,
- botenya ba mofuta oa monna, ka boima ba 'mele o kaholimo. Joalo ka phaello efe kapa efe e feteletseng ea boima ba 'mele, e ka baka lefu la tsoekere.
Uterine endometrial hyperplasia
Ponahalo ea matšoao a "monna" ho basali e lokela ho hlokomelisa le ho sebeletsa e le lebaka la ho etela ngaka ea endocrin ho ea hlahloba boemo ba hau ba dihydrotestosterone.
Mathata ana kaofela a ka lokiseha haeba semelo sa li-hormone se hlophisitsoe ka nako le ka nepo.
Ke hloka ho itokisetsa tlhahlobo
Tsela efe kapa efe e qala ka mohato oa pele, 'me kalafo efe kapa efe e nang le lefu lena Teko ea mali bakeng sa li-hormone ke mohato oa pele oa ho fumana lisosa tsa tlhahiso e feteletseng ea dihydrotestosterone. Tlhahlobo ha e hloke boitokiso bo khethehileng ho mosali, empa ho bohlokoa ho tseba hore o inehela hoseng ka mpa e se nang letho.
Ho khothalletsoa ho etsa thuto ena ka letsatsi la 6-7 la potoloho ea "mosali".
Letsatsi pele u ea laboratoring, o lokela ho:
- tlohela ho tsuba
- qolla lijo tse mafura le tse halikiloeng lijong,
- qoba khatello ea maikutlo le ho ikoetlisa ka ho feteletseng.
Ngaka e eang teng e lokela ho tseba meriana eohle eo mosali a ntseng a e tlhatlhobo. Tse ling tsa tsona li kanna tsa hlakoloa hanyane.
Ho eketseha ha dihydrotestosterone ho basali - kalafo
Mekhoa ea ho sebetsana le ho ata ha dihydrotestosterone e itšetlehile ka mabaka a ileng a e hlahisa, 'me e khethoa ka bonngoe.
Haeba ho se leka-lekane ha lihormone ho ipapisitse le mathata a sebetsang a litho tsa (ka mohlala, sebete), kalafo e qala ka ho khutlisetsa mesebetsi ea bona.
Maemong a mang, ho sebelisoa phekolo ea phetisetso ea li-hormone: li-estrogens li laetsoe hore li khelose ketso ea androgens, ho imolla mosali oa matšoao a "monna". Ho etsa hore boemo ba lihormone tsa banna bo fetohe 'meleng oa basali, lithethefatsi tse kang:
- Diethylstilbestrol ke estrogen e kopaneng.
- Diane 35 ke litokisetso tse kopaneng tsa estrogenic le antiandrogenic.
- Dexamethasone ke synthetic glucocorticoid e thatafatsang protein, carbohydrate le mineral metabolism.
- Cyproterone ke androgen receptor blocker e fokotsang litlamorao tsa li-hormone tsa banna 'meleng.
Hoa etsahala hore phekolo ea lihormone e ngolisitsoe ho ngoanana. Ebe ho khethoa Veroshpiron. E sebetsa ka tsela eo maikutlo a 'mele a amanang le dihydrotestosterone a koetsoeng feela. Lenane la lihormone, ho hang, ha le fokotsehe, empa boteng ba lona maling ha bo ame letho.
Haeba sesosa sa sekhahla sa androgens se eketsehile ka lebaka la mekhoa ea tumor, joale ho etsoa qeto mabapi le ho tlosoa ha tumello. Kahoo, bothata ba dihydrostestosterone e ngata bo tlosoa.
Basali ba nang le botenya ba li-degrees tse fapaneng mme ba tšoeroe ke dihydrotestosterone e ngata ba hloka ho qala kalafo ka mehato e reretsoeng ho theola boima ba 'mele: ho fetola lijo le ho kenyelletsa kemiso e ikhethileng ea' mele morerong oa bona oa letsatsi le letsatsi.
Hoa khoneha ho susumetsa ho fokotseha hoa boemo ba dihydrotestosterone ka lijo tse khethehileng tse nang le lihlahisoa tse phahameng tsa estrogen:
- liapole le cherries ea limaraka tse fapaneng,
- litapole, lihoete le meroho e meng,
- lihlahisoa tsa nama le soya,
- lijo-thollo (koro le raese),
- skim lebese le tranelate
- tsoekere.
Ntle le kalafo ea kajeno ea bongaka, ho na le mekhoa ea bongaka ea setso. Ba-Herbalists ba bolela hore ho nka li-tincture le li-decoctions tsa limela li ka ama boemo ba lihormone hantle, ho e khutlisetsa maemong a tloaelehileng.
Ha ba bua ka polelo ena, litsebi tsa bongaka li eketsa hore ts'ebeliso ea mekhoa e meng ea kalafo molemong ona e ka fana ka phello e ntle feela ka ho se leka-lekane ha li-hormone.
Dihydrostestosterone 'meleng oa basali e ikarabella bakeng sa kholo ea libido le ea moriri.Mabapi le seo e lokelang ho ba tloaelo ea dihydrotestosterone maling a mosali, e bale sengoloa sena.
Mekhoa e ka sehloohong ea ho eketsa testosterone ho basali e hlalositsoe sehloohong sena.
Ho molemo ho kopanya litlhare tsa litlama le litlama tse boletsoeng ke ngaka ea hau - Ho tla ba le molemo o mongata. Ntho ea bohlokoa ha se ho inahanela, ho khetha "litokisetso tsa setso" le ho beha litekanyetso tsa bona ka mokhoa oo u batlang.
Ka tsela, e 'ngoe ea mekhoa e bonolo le e sebetsang ea ho thibela tlhahiso ea dihydrotestosterone e nkoa e tloaelehile ho motho e mong le e mong tee ho tsoa peppermint e tloaelehileng.
'Mele oa mosali le tloaelo ea qoqotho ea lihormone
Bakeng sa ts'ebetso e tloaelehileng ea 'mele, ho leka-lekana ha li-hormone ho bohlokoa. Ho ba teng ha estrogen ho thusa ho nts'etsopele ea kemiso ea kemolo, botsitso ba kemiso ea ho ea matsatsing. Dihydrotestosterone ho basali e etsa mesebetsi e mengata:
Hormone ena e hlahisoa ke litšoelesa le mae a adrenal. E hlokahala ke mmele ka tekanyo e nyane. Tekanyo ea dihydrotestosterone ho basali e itšetlehile ka lilemo le ho tloha ho 24 ho isa ho 450 pg / l.
Keketseho ea DHT e ama 'mele hang hang.
Matšoao a ho eketseha ha DHT: ho kuta moriri le ba bang
Pele ho tsohle, litho tsena tse amang ka ho toba DHT lia ameha. Mohlala, dihydrotestosterone le tahlehelo ea moriri ho basali li amana ka kotloloho. Ena ke bothata bo atisang ho kopana le maemo a eketsehang a hormone ena. Haeba li-hormone li bokellana ho li-bulbs, ts'ebetso ea bona ea mpefala, e leng ho etsang hore moriri e be serethe le mafura. Kamora moo, sena se lebisa tahlehelong ea bona.
Ho fetella ha DHT ho boetse ho ama letlalo le keketseho ea litaba tsa mafura ka lebaka la ho sitisoa ha metabolic. Sena se baka botenya, haholoholo mmeleng o kaholimo.
Bothata bo bong bo iponahatsang ka keketseho ea boemo ba dihydrotestosterone ho banna le basali ke tsoelo-pele ea lefu la tsoekere. Sena se bakoa ke taba ea hore tsoekere ea glucose e rarahaneng bakeng sa lisele.
Bakeng sa banana ba lilemong tsa bocha, keketseho ea DHT maling e baka phetoho ea kholo ea masapo ho ea mothong oa monna. Ntle le moo, banana ba na le ho kopanya lentsoe, tlolo ea potoloho kapa ho ba sieo ka botlalo ho ea khoeling. Bakeng sa basali ba baholo, sena se ka baka ts'ebetso e mpe ea ts'ebetso ea ho ikatisa, ho fihlela kholong ea bokhachane.
Ho eketseha ha maemo a li-hormone ho etsahala:
Lebaka la keketseho ea dihydrotestosterone ho banna le basali e ka ba tlolo ea sebete. Mmele ona o hlahisa globulin, eo limolek'hule tsa eona li sebelisanang le lihormone tsa thobalano.
Haeba maemo a phahameng a DHT a phehella nako e telele, sena se ka lebisa ho mathata a tebileng. Boemong bona, boemo ba 'mele bo hakanyetsoa ke litsebi ka mokhoa o hlakileng.
Ke liteko life tseo u lokelang ho li nka le ho li itokisetsa
Haeba ngaka e belaela keketseho ea boemo ba DHT maling, o khetha tlhahlobo e khethehileng.
Sena se tla khetholla boemo ba li-hormone le mabaka a ho eketseha ha eona. Fuoa tlhahlobo ha mokuli a le:
Ntle le moo, bacha ba fana ka tlhahlobo ena ho tseba hore na lihormone li ba le phello efe kholisong ea sistimi ea kemolo.
Ha a hloke koetliso e khethehileng. Pokello e etsahala hoseng ka mpa e se nang letho. Lingaka li eletsa hore ho se sebelisoe tšebeliso ea lijo tse mafura le tse halikiloeng, ho tsuba, ho ikoetlisa ka matla pele o etsa tlhahlobo.
Tsebisa ngaka ka ho nka meriana. Maemong a mang, ho khothalletsoa ho emisa tšebeliso ea bona matsatsi a 'maloa pele ho pokello ea liteko.
Phekolo ea maemo a phahameng a DHT: mokhoa oa ho theola ts'ebetso ea lithethefatsi le litlhare tsa batho
Phekolo e khethoa ka bonngoe, ho latela lisosa tsa lefu lena. Haeba dihydrotestosterone e phahame ho mosali ea rerileng ho ima, joale o fuoa meriana hore a khothaletse ho ba le li-ovulation.
Ho seng joalo, lithethefatsi tsa lihormone li sebelisetsoa ho thibela kemolo.Li na le phello e sithabetsang ho androgens.
Maemong moo sesosa sa lefu lena ke ho se lekane ha glucose ea lisele, hammoho le boima bo eketsehileng, ho fanoa ka lijo tse tlase tsa carb e le kalafo. E tla u lumella ho tlosa lipolao tse eketsehileng le ho fokotsa boholo ba lihormone.
Bakeng sa mafu a mang a rarahaneng a bakang keketseho ea boemo ba dihydrotestosterone ho basali: kalafo ka metformin, le gynecology ka spironolactone. Ho sebetsa ha bona ka lebaka la thibelo ea phetoho ea testosterone ho DHT.
Bakeng sa kalafo e phethahetseng le e sebetsang, ho hlokahala hore ho hlahlojoe le ho fumana litlhahiso tsa setsebi sa endocrinologist.
Dihydrotestosterone ea ho se leka-lekane ha banna le hore na ho etsoa joang ka keketseho
Dihydrotestosterone ke hormone ea bohlokoa haholo bakeng sa 'mele oa monna. Ke sehlahisoa sa motsoako oa testosterone le li-enzyme tse sebetsanang le eona.
O ikarabella bakeng sa ho holisa, ho hola litho tsa botona le botšehali.
Ho hlahisoa ha DHT ho hlaha litekong, 'me ntho e phahameng ka ho fetesisa e tsepamisitsoe karolong ea epithelial ea genitals le follicles ea moriri.
Dihydrotestosterone e teng 'meleng oa basali le banna, esita le ho tloha nakong ea ho ba ka popelong. Ha nako ea bophelo e ntse e tsoela pele, ho banna palo ea bona e eketseha ka maqhubu.
Bekeng ea pele kamora ho hlaha, boemo ba lihormone ho bashanyana bo tloha ho 2,5 ho isa ho 10 μm / L, ebe oa fokotseha ho fihlela a le lilemo li tharo litaba tsa hae li le hoo e ka bang 0.6 μm / L.
Ka lilemo tse 6, boleng bo nyolohela ho 5 μm / l, mme ka 8 e fokotseha ka halofo. Nakong ea bocha, ho kenella ha 'ona maling ho ea butle butle ho tloha ho 2,5 ho isa ho 10 microns / litha.
Boleng bo phahameng ka ho fetisisa ba dihydrotestosterone bo fihlella ka nako ea lilemo tse 25, kamora moo ho theoha ho ka bang 2 - 3% ka selemo.
Ha lesea le sa le ka popelong le ntse le le ka popelong, ntho eo e ama tsoelo-pele ea litopo le litho tsa ka ntle tsa mpa. Nakong ea bokhachane, boemo ba DHT bo eketseha, litekolo lia hlohlelletsoa, liphatsa tsa lefutso lia nts'etsapeleha, mekhoa ea bobeli ea thobalano e ntse e theoa, 'me tlhahiso ea monna e qala.
Dihydrotestosterone 'meleng oa monna e tsosa tšebetso ea methapo, tšebetso ea litšoelesa tsa sebaceous le li-follicles tsa moriri, li ikarabella bakeng sa kholo ea moriri. Hormone e bohlokoa bakeng sa ts'ebetso e tloaelehileng ea ts'ebetso ea ho ikatisa, e ikarabella bakeng sa takatso ea thobalano, maikutlo a ho tsosa takatso ea botona kapa ea botšehali.
Tloaelo ea ntho ena ea steroid maling e fapana ho latela lilemo, 'me e fokotseha haholo ho banna ba baholo. Haeba boemo ba DHT bo kheloha tloaelo bonyenyaneng, sena se lebisa liphellong tse fapaneng, ho kenyelletsa le adenoma ea Prostate.
Kheloha ho hlaha joang?
Mokhoa oa li-DHT oa 'mele' meleng oa monna oa fokotseha 'me matšoao a bonahala a bontša ho se lekane le ho haella ha ona. Bakeng sa taolo, litsebi li thehile tloaelo lilemong tsohle, ho latela lintlha tse fapaneng. Ho fokotseha kapa keketseho, e lebisang ho khelohileng 'meleng.
Boleng bo tlase ba hormone ena bo lebisa ho:
- lieha ho kena bohlankaneng kapa boroetsaneng,
- ho hloka litšobotsi tsa thobalano,
- lelefatsa
- letheka
- fokotseha ha boima ba mesifa
- fokotsa sex sex,
- ho hloka matla
- ho hloka thari
- botenya
- lefu la tsoekere
- Prostate adenoma
- ho haella ha libido
- mekhelo ea tsamaiso ea genitourinary.
Haeba litaba tsa DHT 'meleng li feta, u ka bona lipontšo tse joalo:
- pelehi
- ho lahleheloa ke moriri ho fihla leqetheng,
- Prostatic hyperplasia,
- hirsutism
- kankere ea senya.
Bakeng sa tlhahlobo e nepahetseng ea mafu, u hloka ho bona ngaka, o tla etsa phuputso e khethollang boemo ba DHT 'meleng.
Dihydrotestosterone e phahame ho banna ba sebelisang li-anabolic tsa steroid ho eketsa boima ba mesifa. Kamora 'kalafo e joalo ea lihormone, testosterone ea mahala e fetoloa estrogen, mme motsoako oa eona oa fokotseha.Kamora 'nete ea lithethefatsi tsa anabolic, boemo ba lihormone tsa basali' meleng oa monna bo nyoloha, boemo bona bo ka lebisa ho se atleheng ha li-hormone.
Litaba tsa DHT maling li eketseha ka mabaka a latelang:
- Lefu la Itsenko-Cushing,
- hlahala e mpe ea litšoelesa kapa li-testicles tsa adrenal,
- Leydig cell hyperplasia,
- tšoelesa ea senya ea senya
- Morris syndrome
- hypergonadism.
DHT e tlase e ka hlaha haeba monna a e-na le bothata ba ho ba le mathata a tlhaho. Haeba 'mele o haelloa ke enzyme 5-alpha-reductase, motsoako oa testosterone ha o hlahe.
Ho bana ba nang le lefu lena la methapo, li-pathologies tsa genital li bonoa.
Ka ho fokotseha ha DHT ea mokuli, bophelo ba thobalano bo fetoha ho se tsotelle, ha a ikutloe a lakatsa ho ba le kamano e haufi, takatso ea thobalano e nyamela.
Bophelo ba thobalano bo amana ka kotloloho le ts'ebetso ea litho tsa botona, kahoo ho fokotseha hoa boleng ba eona ho ka lebisa ho atrophy ea botoneng.
Ho fokotseha ha qoqotho ea lihormone tse nang le botsofali ho tletse liphapang tsa ts'ebetso ea ts'ebetso ea methapo, methapo ea methapo ea mali le pelo.
Litlhare tsa setso
Hape, litlolo tse joalo tsa setso li tla thusa ho theola boemo ba lihormone tsa banna:
- K'habeche e sa tsoa omisoa - lero la celery, leo u hlokang ho le noa letsatsi le letsatsi, khalase e le 1 ka mpa e se nang letho. Kapa u ka chenchana ho nka rantipole le celery, thupelo ke libeke tse peli.
- Tee e nang le licorice.
Hoa hlokahala ho khaola motso oa licorice ka mokhoa o hlakileng, ho eketsa makhasi a tee le ho noa senoelo sa tee pele u robala matsatsi a 14. Tincture ea peo ea folaxe. Nka 1 tbsp. l lipeo, tšela halofo ea khalase ea metsi a belang, lihora tse 'maloa, sebelisa 1 tbsp. l ka letsatsi ka mpeng e se nang letho.
Pele o sebelisa kalafo ea setso, o hloka ho buisana le setsebi.
Dihydrotestosterone 'meleng e bapala karolo ea bohlokoa haholo, e nka karolo lits'ebetsong tse ngata,' me ho kheloha ha eona ho latela tloaelo ho ka lebisa ho li-pathologies le mafu a mangata.
Ka lebaka lena, ho bohlokoa haholo ho hlokomela bophelo bo botle ba hau le ho ela hloko matšoao a alamo a bonts'a ho ba teng ha mekhoa.
Ha u se u hlokometse matšoao a bokuli ba li-hormone, o hloka ho batla thuso ea bongaka e tšoanelehang.
Li-dihydrotestosterone li eketseha joang ho basali le hore na ba ka ntlafatsa matšoao a sebopeho sa testosterone joang?
Lihormone tse ngata tsa banna 'meleng oa basali li ama boima ba' mele, ho potoloha ha banna, bokhoni ba ho ima, likarolo tsa ponahalo, metabolism ea carbohydrate.
Ka ts'ebetso e sa lokelang ea mae a bomme le litšoelesa tsa adrenal, khatello ea "testosterone" feela, empa le androgen ea bobeli e sebetsang e eketseha. Dihydrotestosterone (DHT) e hlahisoa ka maeeng le adrenal cortex.
Ho kheloha boemong ba lihormone tsa banna ho bontša ka potlako boemo ba 'mele.
Seo u lokelang ho se etsa haeba dihydrotestosterone e phahame ho basali? Lisosa le matšoao a hyperandrogenism, litlamorao tse ka bang teng, mekhoa ea kalafo le thibelo ea methapo ea mafu li hlalositsoe sehloohong seo.
Karolo ea li-hormone tsa monna 'meleng oa mosali
Sebopeho se nang le bioactive sa testosterone se ameha ho tsamaisong ea mekhoa e mengata:
- E boloka letsoalo le lekaneng la masapo, e tšehetsa ho ntlafatsoa ha mesifa,
- Ho thibela ho suna hoa mesifa,
- e ama matla a libido,
- e fana ka mafura a loketseng hantle,
- e laola ho sebetsa ha litšoelesa tsa sebaceous.
Dihydrotestosterone (DHT) e sebetsa haholo ho feta li-androgens tse ling. Ho haella ha molaoli oa bohlokoa ho lebisa ho liphetoho tse sa lokang 'meleng oa mosali.
Androgen e ngata haholo e boetse e ama hampe mokhoa oa ho ikatisa, ponahalo le tšebetso ea 'mele.
Ho fapana le testosterone, DHT ha e fetole liphetoho, ha e fetoloe ho estrogens mme e thibela phetoho e tšoanang ea testosterone ho eketsa khatello ea lihormone tsa basali tsa thobalano.
Mabaka a kheloha
Ho kheloha hofe kapa hofe ho boemo ba DHT 'meleng oa monna ho bontša tsoelo-pele ea li-pathologies.Ebile, bakeng sa bophelo bo botle ba mokuli, matšoao a phahameng haholo le litlamorao tse tlase li kotsi.
Dihydrotestosterone ea ho se leka-lekane ha banna le hore na ho etsoa joang ka keketseho
Dihydrotestosterone ke hormone ea bohlokoa haholo bakeng sa 'mele oa monna. Ke sehlahisoa sa motsoako oa testosterone le li-enzyme tse sebetsanang le eona.
O ikarabella bakeng sa ho holisa, ho hola litho tsa botona le botšehali.
Ho hlahisoa ha DHT ho hlaha litekong, 'me ntho e phahameng ka ho fetesisa e tsepamisitsoe karolong ea epithelial ea genitals le follicles ea moriri.
Dihydrotestosterone e teng 'meleng oa basali le banna, esita le ho tloha nakong ea ho ba ka popelong. Ha nako ea bophelo e ntse e tsoela pele, ho banna palo ea bona e eketseha ka maqhubu.
Bekeng ea pele kamora ho hlaha, boemo ba lihormone ho bashanyana bo tloha ho 2,5 ho isa ho 10 μm / L, ebe oa fokotseha ho fihlela a le lilemo li tharo litaba tsa hae li le hoo e ka bang 0.6 μm / L.
Ka lilemo tse 6, boleng bo nyolohela ho 5 μm / l, mme ka 8 e fokotseha ka halofo. Nakong ea bocha, ho kenella ha 'ona maling ho ea butle butle ho tloha ho 2,5 ho isa ho 10 microns / litha.
Boleng bo phahameng ka ho fetisisa ba dihydrotestosterone bo fihlella ka nako ea lilemo tse 25, kamora moo ho theoha ho ka bang 2 - 3% ka selemo.
Ha lesea le sa le ka popelong le ntse le le ka popelong, ntho eo e ama tsoelo-pele ea litopo le litho tsa ka ntle tsa mpa. Nakong ea bokhachane, boemo ba DHT bo eketseha, litekolo lia hlohlelletsoa, liphatsa tsa lefutso lia nts'etsapeleha, mekhoa ea bobeli ea thobalano e ntse e theoa, 'me tlhahiso ea monna e qala.
Dihydrotestosterone 'meleng oa monna e tsosa tšebetso ea methapo, tšebetso ea litšoelesa tsa sebaceous le li-follicles tsa moriri, li ikarabella bakeng sa kholo ea moriri. Hormone e bohlokoa bakeng sa ts'ebetso e tloaelehileng ea ts'ebetso ea ho ikatisa, e ikarabella bakeng sa takatso ea thobalano, maikutlo a ho tsosa takatso ea botona kapa ea botšehali.
Tloaelo ea ntho ena ea steroid maling e fapana ho latela lilemo, 'me e fokotseha haholo ho banna ba baholo. Haeba boemo ba DHT bo kheloha tloaelo bonyenyaneng, sena se lebisa liphellong tse fapaneng, ho kenyelletsa le adenoma ea Prostate.
Kheloha ho hlaha joang?
Mokhoa oa li-DHT oa 'mele' meleng oa monna oa fokotseha 'me matšoao a bonahala a bontša ho se lekane le ho haella ha ona. Bakeng sa taolo, litsebi li thehile tloaelo lilemong tsohle, ho latela lintlha tse fapaneng. Ho fokotseha kapa keketseho, e lebisang ho khelohileng 'meleng.
Boleng bo tlase ba hormone ena bo lebisa ho:
- lieha ho kena bohlankaneng kapa boroetsaneng,
- ho hloka litšobotsi tsa thobalano,
- lelefatsa
- letheka
- fokotseha ha boima ba mesifa
- fokotsa sex sex,
- ho hloka matla
- ho hloka thari
- botenya
- lefu la tsoekere
- Prostate adenoma
- ho haella ha libido
- mekhelo ea tsamaiso ea genitourinary.
Haeba litaba tsa DHT 'meleng li feta, u ka bona lipontšo tse joalo:
- pelehi
- ho lahleheloa ke moriri ho fihla leqetheng,
- Prostatic hyperplasia,
- hirsutism
- kankere ea senya.
Bakeng sa tlhahlobo e nepahetseng ea mafu, u hloka ho bona ngaka, o tla etsa phuputso e khethollang boemo ba DHT 'meleng.
Dihydrotestosterone e phahame ho banna ba sebelisang li-anabolic tsa steroid ho eketsa boima ba mesifa. Kamora 'kalafo e joalo ea lihormone, testosterone ea mahala e fetoloa estrogen, mme motsoako oa eona oa fokotseha. Kamora 'nete ea lithethefatsi tsa anabolic, boemo ba lihormone tsa basali' meleng oa monna bo nyoloha, boemo bona bo ka lebisa ho se atleheng ha li-hormone.
Litaba tsa DHT maling li eketseha ka mabaka a latelang:
- Lefu la Itsenko-Cushing,
- hlahala e mpe ea litšoelesa kapa li-testicles tsa adrenal,
- Leydig cell hyperplasia,
- tšoelesa ea senya ea senya
- Morris syndrome
- hypergonadism.
DHT e tlase e ka hlaha haeba monna a e-na le bothata ba ho ba le mathata a tlhaho.Haeba 'mele o haelloa ke enzyme 5-alpha-reductase, motsoako oa testosterone ha o hlahe.
Ho bana ba nang le lefu lena la methapo, li-pathologies tsa genital li bonoa.
Ka ho fokotseha ha DHT ea mokuli, bophelo ba thobalano bo fetoha ho se tsotelle, ha a ikutloe a lakatsa ho ba le kamano e haufi, takatso ea thobalano e nyamela.
Bophelo ba thobalano bo amana ka kotloloho le ts'ebetso ea litho tsa botona, kahoo ho fokotseha hoa boleng ba eona ho ka lebisa ho atrophy ea botoneng.
Ho fokotseha ha qoqotho ea lihormone tse nang le botsofali ho tletse liphapang tsa ts'ebetso ea ts'ebetso ea methapo, methapo ea methapo ea mali le pelo.
Ts'oaetso
Haeba motho a eketsehile ka dihydrotestosterone, sena se bontša maloetse a itseng. Bakeng sa ho fumana hore na lihormone li kae, ho etsoa tlhahlobo ea mali.
Haeba monna a e-na le benign prostatic hyperplasia, joale ho etsoa phuputso e le ho shebella maemo le ho latela liphetoho ha a sebelisa meriana ka moriana o fokotsang 5-alpha.
Tlhatlhobo e tlameha ho nkuoa hoseng ho tloha lihora tse 8 ho isa ho tse 11, ka mpeng e se nang letho. Pele u tlisoa, u ka noa metsi a hloekileng a ntse a le metsi, u se ke ua a nwa tee, lero le tsoekere. Mantsiboea u ke ke ua ja lijo tse mafura, tse tsubang le tse nokiloeng ka linoko.
Matsatsi a 1 - 2 pele a nka tlhahlobo, ho a hlokahala hore a kenyeletse ho se noe joala le ho tsuba, ho ikoetlisa ka matla ho kenyeletsa ho phahamisa boima le lipapali tse mafolofolo. Hoa hlokahala ho khaotsa ho sebelisa meriana, empa feela ka mor'a ho buisana le ngaka.
Bosiung ba tlhahlobo, maemo a sithabetsang a tlameha ho qojoa, hobane hora ka pel'a hae o hloka ho theola maikutlo le ho phomola.
Ho phehelloa ho khanna thuto ka mor'a ho etsa lipatlisiso ka matla ka X-ray le X-ray, hammoho le ho silila le physiotherapy. E fetisoa ka mor'a nako e itseng makhetlo a 'maloa. Ho latela maemo a maemo le nako ea nehelano ea tlhahlobo e tlameha ho ts'oana hantle.
Ho nka meriana e itseng ho ka khopamisa sephetho sa tlhahlobo, ka hona, menyetla ea bona e lokela ho buisanoa le ngaka ea hau.
Khethong ea ngaka
Phekolo ea sejoale-joale ha e so ithute mokhoa oa ho felisa sesosa sa pherekano ea lihormone 'meleng, empa ho bohlokoa ho thathamisa boemo ba DHT maling ka nako.
Haeba u iphumana u phahamisa kapa u theola khatello ea maqhubu a lihomone, ho kgothaletsoa ho ikopanya le urologist le endocrinologist.
Mekhoa ea ho theola lihormone 'meleng e amana ka ho toba le sesosa sa keketseho, litšobotsi tsa setšoantšo sa kliniki le boemo bo akaretsang ba mokuli.
Lisebelisoa tsa kalafo le li-regimen tsa kalafo li laetsoe ka bonngoe, sena se khetholloa ke 'nete ea hore lits'ebetso tsa li-hormone' meleng li hokahane.
Ke setsebi feela se tsebang lintlha tsohle tsa tsamaiso ea endocrine, hape a ka khetha kalafo. Maemong a mangata, lithethefatsi li laetsoe ho ela hloko tlhahiso ea hau ea lihormone.
Phekolo ea banna e khethoa e felletse e sebelisa mekhoa le lisebelisoa tse fapaneng.
Mohlala, bakuli ba nang le dihydrotestosterone e phahameng ho feta e tloaelehileng ba fuoa meriana ea inhibitory bakeng sa 5-alpha reductase bakeng sa ho fokotsa synthesis ea testosterone.
Tsena li kenyelletsa Suprefact, Deslorelin, Buserelin, Medroxyprogesterone, Veraplex, Spironolactone.
Empa ho bohlokoa ho tseba hore ke ngaka feela e nang le boiphihlelo e ka fanang ka litlhare le hore na nako ea taolo e kae, kalafo ea boits'oaro e lebisa ho se leka-lekanang ha li-hormone, e mpefatsa boemo mme e kotsi bophelong.
Litlhare tsa setso
Hape, litlolo tse joalo tsa setso li tla thusa ho theola boemo ba lihormone tsa banna:
- K'habeche e sa tsoa omisoa - lero la celery, leo u hlokang ho le noa letsatsi le letsatsi, khalase e le 1 ka mpa e se nang letho. Kapa u ka chenchana ho nka rantipole le celery, thupelo ke libeke tse peli.
- Tee e nang le licorice.
Hoa hlokahala ho khaola motso oa licorice ka mokhoa o hlakileng, ho eketsa makhasi a tee le ho noa senoelo sa tee pele u robala matsatsi a 14. Tincture ea peo ea folaxe. Nka 1 tbsp. l lipeo, tšela halofo ea khalase ea metsi a belang, lihora tse 'maloa, sebelisa 1 tbsp. l ka letsatsi ka mpeng e se nang letho.
Pele o sebelisa kalafo ea setso, o hloka ho buisana le setsebi.
Dihydrotestosterone 'meleng e bapala karolo ea bohlokoa haholo, e nka karolo lits'ebetsong tse ngata,' me ho kheloha ha eona ho latela tloaelo ho ka lebisa ho li-pathologies le mafu a mangata.
Ka lebaka lena, ho bohlokoa haholo ho hlokomela bophelo bo botle ba hau le ho ela hloko matšoao a alamo a bonts'a ho ba teng ha mekhoa.
Ha u se u hlokometse matšoao a bokuli ba li-hormone, o hloka ho batla thuso ea bongaka e tšoanelehang.
Li-dihydrotestosterone li eketseha joang ho basali le hore na ba ka ntlafatsa matšoao a sebopeho sa testosterone joang?
Lihormone tse ngata tsa banna 'meleng oa basali li ama boima ba' mele, ho potoloha ha banna, bokhoni ba ho ima, likarolo tsa ponahalo, metabolism ea carbohydrate.
Ka ts'ebetso e sa lokelang ea mae a bomme le litšoelesa tsa adrenal, khatello ea "testosterone" feela, empa le androgen ea bobeli e sebetsang e eketseha. Dihydrotestosterone (DHT) e hlahisoa ka maeeng le adrenal cortex.
Ho kheloha boemong ba lihormone tsa banna ho bontša ka potlako boemo ba 'mele.
Seo u lokelang ho se etsa haeba dihydrotestosterone e phahame ho basali? Lisosa le matšoao a hyperandrogenism, litlamorao tse ka bang teng, mekhoa ea kalafo le thibelo ea methapo ea mafu li hlalositsoe sehloohong seo.
Karolo ea li-hormone tsa monna 'meleng oa mosali
Sebopeho se nang le bioactive sa testosterone se ameha ho tsamaisong ea mekhoa e mengata:
- E boloka letsoalo le lekaneng la masapo, e tšehetsa ho ntlafatsoa ha mesifa,
- Ho thibela ho suna hoa mesifa,
- e ama matla a libido,
- e fana ka mafura a loketseng hantle,
- e laola ho sebetsa ha litšoelesa tsa sebaceous.
Dihydrotestosterone (DHT) e sebetsa haholo ho feta li-androgens tse ling. Ho haella ha molaoli oa bohlokoa ho lebisa ho liphetoho tse sa lokang 'meleng oa mosali.
Androgen e ngata haholo e boetse e ama hampe mokhoa oa ho ikatisa, ponahalo le tšebetso ea 'mele.
Ho fapana le testosterone, DHT ha e fetole liphetoho, ha e fetoloe ho estrogens mme e thibela phetoho e tšoanang ea testosterone ho eketsa khatello ea lihormone tsa basali tsa thobalano.
Mabaka a kheloha
Secretion e eketsehang ea dihydrotestosterone ke litholoana tsa ts'ebetso ea methapo ea methapo 'meleng oa mosali. Haeba boemo bo eketsehileng ba androgen bo fumanoa ho banana ba lilemong tsa bocha nakong ea kemolo ea ho ea matsatsing, joale ketsahalo ena e lumelletsoe ha ho hlophisoa ha lihormone ho ntse ho tsoela pele. Butle-butle, boemo ba lihomone tsa banna bo lokela ho atamela ka tsela e tloaelehileng.
Haeba mokelikeli o sa khahlise, lilemo tse 1-2 kamora ho qala ho ea khoeling, o hloka ho ikopanya le ngaka ea mafu a basali ho hlakisa boemo ba androgens. Khahlano le semelo sa tokiso e sa lebelloang ea semelo sa lihormone, ka litekanyetso tse phahameng tsa DHT, hoa khonahala ho nts'etsapele mahe a polycystic, bokhachane, hirsutism, mathata a nang le boemo ba moriri le letlalo.
Ithute ka matšoao a pele le matšoao a kankere ea tšoelesa ea senya.
Bala ka TAB ena ea "thyroid gland node" le hore na tlhahlobo ea tlhahlobo ea mafu e etsoa joang ho bala atereseng ena.
Lisosa tse ling tsa litekanyetso tsa dihydrotestosterone tse eketsehang:
- benign tumor ea gland kapa mae a bomme,
- phatsa ea tlhaho
- boimana
- ho se utloisisehe hantle ha tsoekere ea glucose, metabolism e fokolisitsoeng ea lik'habohaedreite.
Liponahatso tsa kliniki
Matšoao a tlhahiso ea dihydrotestosterone e ngata:
- lentsoe le ea tlaase le ho honyela
- skeleton nakong ea bongoaneng e hlaha ho ea ka mofuta oa monna,
- ho ea matsatsing ho fetoha ho fokola, ho sa tloaelehang, kapa amenorrhea ho hlaha (ho se be le ho tsoa madi khoeli le khoeli),
- moriri o ea fokotseha, oaonda, alopecia hangata e hlaha,
- Ho sitisoa ha lits'ebetso mokhoeng oa ho ea matsatsing ho kena-kenana le phetoho ea li-follicles, ho lokolloa ha lehe. Ntle le ovulation, mohopolo ha o khone,
- matsohong le maotong, moriri o mosoeu o oa totobala ebe o fifala, ho hlaha hirsutism, limela tse sa batleheng li hlaha kaholimo ho molomo le sebakeng sa sefahleho.
- boima bo tla eketseha ka potlako
- ho na le litlhaselo tsa ho teneha le mabifi a se nang mabaka,
- ts'ebetso ea litšoelesa tsa sebaceous ea eketseha, letlalo le fetoha oli, makhopho a hlaha,
- bokima ba lera la mafura lethekeng le thekeng le ea fokotseha, mokuli ha a sa na basali.
Hlokomela! Tloaelo ea dihydrotestosterone ho basali e tsoa ho 24 ho isa ho 450 pg / ml. Matšoao a tlase haholo ho feta ho banna (ho tloha ho 250 ho isa ho 990 pg / ml).
Liphello tse ka bang teng
Ho fetella ka nako e telele litekanyetso tsa dihydrotestosterone ho basali ho ka lebisa litlamorao tse sa rateheng:
- hirsutism
- amenorrhea
- menstrual irregularities,
- Phetoho sebopehong sa ho ea matsatsing,
- lefu la tsoekere
- moriri o mafura le letlalo,
- Moriri o motenya,
- tahlehelo ea botšehali
- molumo oa lentsoe
- ho hloka boroko
- metabolism e sa foleng ea carbohydrate, nts'etsopele ea lefu la tsoekere,
- botenya
- polycystic ovary syndrome,
- dysfunction.
U ka etsa patlisiso joang ho DHT
Ho hlakisa boemo ba dihydrotestosterone, mosali o lokela ho tla laboratoring karolong ea pele ea potoloho. Nako e nepahetseng e tsoa matsatsing a mane ho isa ho a tšeletseng.
Melao ea ho lokisa:
- pele ho tlhahlobo (nakong ea letsatsi) u ke ke ua noa joala, ho eletsoa hore u se ke ua tšoha. Se ke oa ikoetlisa kapa ua etsa mosebetsi oa jareteng, mosebetsi o boima,
- letsatsi pele ho thuto, lijo e lokela ho ba tse bobebe, tse nonneng haholo,
- hoseng u ka se noe 'me u je,
- Lithethefatsi tsohle li tlameha ho nkuoa kamora ho fetisa tlhahlobo ea dihydrotestosterone,
- ho etela laboratoring hoa hlokahala hoseng, pele ho feta lihora tse 11,
- pele o nka mali, o hloka ho theola moea, ho phomola ofising ka metsotso e 15-20,
- ka letsatsi la thupelo (pele ho sampole ea mali ea venous) ho ke ke ha khoneha ho etsa ECG, X-ray le fluorogram, ho fumana massage le physiotherapy.
Litsela tsa ho nolofatsa maemo a li-hormone
Ha o senola litheko tse phahameng tsa dihydrotestosterone, o hloka ho fumana sesosa sa liphapang. Kamora ho tlosa ntho e tenang, o hloka ho fetola mokhoa oa ho ja, ho tsitsisa boima ba mmele ho etsa hore metabolism ea carbohydrate le ho leka-lekana ha li-hormone. Etsa bonnete ba ho fokotsa mojaro tsamaisong ea methapo, ho khutlisa botsitso ba kelello le maikutlo.
Ngaka e lokela ho hlakisa hore na mokuli o sebelisa lithethefatsi life. Haeba lithethefatsi li fumanoa tse khothaletsang tlhahiso ea dihydrotestosterone, joale ho hlokahala hore u khethe li-analogues kapa u hane ho sebelisa lithethefatsi tse eketsang boemo ba androgen.
Ho latela khetho ea ngaka ea methapo ea kutlo kapa gynecologist, ho bohlokoa ho latela tsela ea phekolo u sebelisa lithibela-pelehi tsa molomo. Lipilisi li fana ka litholoana tse ntle: Janine, Yarina. Ka ho kheloha hanyane ho DHT ho tloha ho tloaelehileng, sethethefatsi Femoden se laetsoe.
Ho fokotsa mokokotlo oa li-hormone tsa botona ba botšehali, mokuli o nka malebela a thehiloeng spironolactone le metformin. Lithethefatsi tse Siofor, Veroshpiron, Glucofage ha li kena feela phetohong ea testosterone ho dihydrotestosterone, empa hape e fokotsa tsoekere ea mali, ho thatafatsa ho ts'oaroa ha glucose le metabolism ea carbohydrate.
Mokhoa oa ho fokotsa testosterone ho basali ba se nang li-hormone ka mekhoa ea tlhaho? Re na le karabo!
Bakeng sa matšoao a khethehileng le kalafo e sebetsang ea Hashimoto's thyroiditis, bala aterese ena.
Leqepheng la http://vse-o-gormonah.com/vneshnaja-sekretsija/grudnye/listovidnaya-fibroadenoma.html ithute ka seo 'mele oa makhasi a sefahleho sa limela tsa mammary le mokhoa oa ho felisa thuto.
Ho fokotsa bongata ba dihydrotestosterone, ho bohlokoa ho sebelisa lihlahisoa tse nang le phytoestrogens:
- lintho tsa lebese tse bolila,
- meroho e makhasi
- koro e ponneng
- oli e halikiloeng le lipeo,
- soya
- cherries
- lijo-thollo
- oli ea limela
- linaoa
- Persimmon
- linate.
Ho tsitsisa botsitso ba lihormone, ho fumana li-phytoestrogens, ho bohlokoa ho noa tee e thehiloeng ho:
- peppermint
- makhasi a lamunu
- Tee ea Ivan
- marigolds
- daisies
- cuffs
- tsimitsifugi
- oregano
- alfalfa
- moluoane
- angelica
- setlhare sa lemone.
Ka nts'etsopele ea hyperandrogenism, ho hlokahala hore ho sekasekoa lintlha tse khahlanong le hore na li-dihydrotestosterone li nyoloha hakae.
Ho hloka botsitso ha khoeli ea ho ea matsatsing, ho eketseha ha moriri ka bongata 'meleng, ho ba mabifi ho feteletseng le ho teneha, le kholo ea botenya ha e na ho hlokomolohuoa.
Ha khatello ea dihydrotestosterone e tsitsa, menyetla ea mathata a bophelo ba ho ikatisa e ea fokotseha, 'me lithibelo tsa ho fokotsa tsoekere ea glucose li fokotsehile.
Dihydrotestosterone (DHT) ho basali: ke eng, tloaelo ea li-hormone, ho ea tlase
Ho fumana hore na dihydrotestosterone ke eng, kaha re utloisitse mesebetsi ea eona ea mantlha 'meleng oa motho.
E 'ngoe ea li-hormone tsa thobalano tsa banna tse bohlokoa ka ho fetisisa ke dihydrotestosterone (DHT). O ikarabella bakeng sa lits'ebetso tsa bohlokoa haholo tse etsahalang 'meleng oa monna:
- ts'ebetso e sebetsang ea prostate
- Ntshetsopele e nepahetseng ea litho tsa botona le tsa ka hare,
- kholo ea mesifa e ts'oanang,
- sebopeho sa tsamaiso ea masapo,
- kholo ea moriri
- o laola boitšoaro ba thobalano le ho ema.
Dihydrotestosterone e boetse e hlahisoa 'meleng oa mosali. Li-hormone tsohle tsa botona ba botšehali li bitsoa androgens 'me li hlahisoa ka har'a litšoelesa tsa adrenal. Lihormone tsa banna li hlokahala hore basali ba:
- metabolism
- kholo ea masapo, mesifa, moriri,
- taolo ea litšoelesa tsa sebaceous le sweat,
- sebopeho sa libido.
Ho kheloha tlhahisong ea dihydrotestosterone ho banna le basali, ka bobeli ka mokhoa oa ho eketsa khatello ea eona, le ka ho fokotseha ha maemo, ho ka lebisa tlolong e kholo ea ketso ea litsamaiso tse fapaneng tsa 'mele.
Sekhahla sa li-hormone ho banna le basali
Ho tseba ho kheloha sephiring sa DHT 'meleng, ho sebelisoa matšoao a eona a tloaelehileng. Khatello e maling e ikemiselitsoe ka ho fetisa tlhahlobo ea bongaka, litekanyetso tse fumanoeng li bapisoa le tse tloaelehileng.
Lethathamo la litloaelo tsa letšoao la dihydrotestosterone ho banna le basali ka lilemo:
Mefuta ea li-hormone e theohileng - lisosa, matšoao, likhetho tsa kalafo
Tlhahiso ea DHT 'meleng oa monna e kanna ea fokotseha tlasa ts'usumetso ea lintlha tse fapaneng:
- dysfunction
- prostatitis
- lefu la tsoekere
- hlahala marang-rang a adrenal,
- khaello ea androgen
- le lefu la Morris,
- hypogonadism - ho haella ha li-gonads.
Hypogonodism ho banna
U ka ela hloko bophelo ba hau bo botle 'me u nka liteko tse bontšang hore na lihormone li qala ho ba le matšoao a latelang.
- ho lahleheloa ke moriri ka tšohanyetso, ho emisa kholo ea bona,
- botenya, bo bonahatsoang ke mofuta oa basali (mpa, sefuba, letheka),
- erectile dysfunction,
- ho haella ha thobalano,
- ho fufuleloa ho eketsehileng
- fokotseha ha boima ba mesifa
- letlalo le omeletseng
- mokhathala, khatello ea maikutlo, ho hloka boroko,
- ho hloka thari
Ka setso, lingaka li eletsa ho ea hlahlojoa haeba ho na le bonyane matšoao a mararo a kaholimo.
Ho bashanyana, boemo bo tlase ba li-hormone bo bonahatsoa ka tsela e latelang:
- ho haella ha mesifa
- kholo ea moriri o liehang, ho ba sieo ha bona sefahlehong, meqomong, monko
- penis e fokotsehile kapa sebopeho sa eona se sa tloaelehang,
- ho na le basali ka bongata,
- ho se sebetse hantle ha litho le matsoho.
Ho eketsa maemo a lihormone?
Khafetsa, boemo bo tlase ba hormone bo bonoa ho banna kamora lilemo tse 30 ho isa ho 40; mafu a fapaneng a ka baka sena. Haeba secretion ea lihormone e fumanoa e le tlase ho e tloaelehileng, ho hlokahala hore u hlahlojoe ka botlalo hore u tsebe li-pathologies tse thata. Phekolo e lokela ho qala ka ho felisoa ha sesosa sa motso.
'Me ho eketsa boemo ba "dihydrotestosterone" ea "hormone", "endocrinologist" e ka fana ka kalafo e khutlisetsoang ka litlhare tsa maiketsetso tse nang le testosterone.
Phetohelo ea testosterone ho Dihydrotestosterone
Ho li-tishu tse arabelang ka androgen, ts'ebetso ea testosterone e eketseha haholo, 'me e qala ho fetolela ho dihydrotestosterone. Ts'ebetso ena e bitsoa phetoho ea testosterone. Enzyme ea 5-alpha reductase e thusa haholo phetolelong ena ka ho eketsa liathomo tse peli tsa hydrogen sebopeho sa testosterone, ke ka lebaka leo hormone e bitsoang di-hydro-testosterone.
Nakong ea phetoho, tlamahano pakeng tsa testosterone le dihydrotestosterone e felisoa, 'me ho thehoa steroid e sebetsang, e nang le tlamo e matla le li-androgen receptors. Ke ka lebaka leo e nang le matla a maholo ho 'mele oa monna kapa mosali.
Hobane ho na le li-hormone tse ngata haholo
Ho ba teng ha Prostate adenoma ke sesosa se atileng haholo sa ho eketseha ha dihydrotestosterone ho banna.
Nakong ea lithuto tsa mahlale tse entsoeng le ho nka karolo ha banna ba lilemo tse 25 ho isa ho tse 40, ho ile ha fumaneha hore motho e mong le e mong ea neng a e-na le tlhahlobo ea lefu la adenoma ea tšoelesa ea senya o ne a eketsehile dihydrotestosterone.
Ka lebaka la nts'etsopele ea makhopho a semmuso a tšoelesa ea senya, e hola ka boholo mme e hlahisa lihormone tse ngata.
Litlamorao tsa keketseho e sa tloaelehang ea secretion ea lihormone 'meleng oa monna:
- lefahla, ho kuta moriri ka tšohanyetso,
- ponahalo ea makhopho
- ho se khonehe
- boitšoaro bo mabifi, bo mabifi
- bokhachane bo hlahisoang khahlanong le testicular atrophy.
Ka ho eketseha ha dihydrotestosterone ho basali, mmele o arabela ka tsela e fapaneng haholo, ho na le:
- kholo e ntlafalitsoeng ea moriri sefahlehong, 'mele, mofuta oa monna,
- ho ruruha ho feteletseng
- secretion e eketsehileng ea litšoelesa tsa sebaceous,
- lefu la metabolic, mme ka lebaka leo - botenya
- ngoanana a ka ikutloa a eketsehile ho khanna ho kopanela liphate,
- ho ilela khoeli
- keketseho ea boholo ba clitoris le labia.
Haeba dihydrotestosterone e phahame ho basali, joale sena se ka supa mafu a tebileng:
- li-adrenal tumors,
- ho hloka thari
- hirsutism.
Mabaka a keketseho ea litekanyo tsa li-hormone ho basali:
- hlahala mahe a mae a bomme,
- khaello ea phepo e nepahetseng, botenya
- ho sebelisa lithethefatsi tse ling tsa lihormone,
- tlhahiso-leseling ea hypothalamus kapa e fumanoeng.
Sensitivity ho dihydrotestosterone e bonoa ho basali ba nang le lefu la tsoekere la mofuta oa 2.
Hormone blocker
Bakeng sa ho fokotsa sekhahla sa dihydrotestosterone, ho hlokahala ho thibela 5-alpha reductase. Ka lebaka la enzyme ena, phetoho ea testosterone ho DHT e etsahala. Dihydrotestosterone le tahlehelo ea moriri ke likhopolo tse peli tse kopaneng, hobane tlhahiso ea enzyme e itšetlehile ka ts'ebetso ea li-follicles tsa moriri.
Ke ka lebaka leo, khahlano le tlhahiso ea li-hormone, moriri o tsoang. Lithethefatsi tse laetsoeng ho theola sekhahla sa dihydrosterone li bitsoa li-blockers tsa 5-alpha reductase. Tse atileng haholo ke:
Ntle le lithethefatsi tsa maiketsetso, phytoestrogens e sebelisoa ho fokotsa tlhahiso ea lihormone:
- litholoana tse nyane tsa palema li na le asiti tse mafura, li-resin le li-tannin, tse fokotsang tšebetso ea li-follicles tsa moriri,
- E khohlela letlapa
- red clover
- soya
- alfalfa.
Li-androgen tsa basali tse theolang lithethefatsi
Haeba dihydrotestosterone ho basali e phahame, ngaka e eang teng e ka fana ka litlhare tse latelang:
Lithethefatsi tsena tse peli ha li thibele tšebetso ea androgens feela, empa li thibela tlhahiso ea tsona.
Khafetsa, lingaka li ka fana ka litlhare tsa thibelo ea bokhachane:
Fokotsa boemo ba lihormone ka tsela ea meriana, ho khothalletsoa ho sebelisa li-decoctions tsa litlama:
Ho eketseha ha dihydrotestosterone ho basali - lisosa le mekhoa ea kalafo
Li-dihydrotestosterone tse phahamisitsoeng ho basali li etsahala ka mabaka a fapaneng.
Maemong a mang, sena se hlalosoa ke mekhoa ea tlhaho ea 'mele, ho ba bang - ke ho ba teng ha li-pathologies' meleng.
Hoa hlokahala ho khetholla ha phetoho ea semelo sa lihormone e le ea nakoana mme e sa behe kotsi, le ha ho hlokahala tlhokomelo ea bongaka.